Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002712
Title: Effect of noni as a pre-procedural rinse in gingivitis patients: A cross-sectional study
Category: Pharmacology
Section: Research Article
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    Aim: Morinda citrifolia (Noni) has been used for decades in traditional Asian medicine. It has a lot of pharmacological properties and clinical implications. It has antibacterial, anti-inflammatory and antimicrobial properties. It can be used in a number of diseases such as cancer, infectious diseases, cardiovascular diseases, diabetes, and also female-specific problems. Noni also exerts its curative effect on gingivitis and periodontitis which are also inflammatory in nature. The most common form of the gingival disease is plaque-induced gingivitis which is caused due to the interaction between bacteria in the dental plaque, the tissues, and inflammatory cells of the host. There have been numerous research studies done in animals and humans to assess the effect of noni. This study was done to assess the effect of noni as a pre-procedural rinse. Materials and Methods: A total of 10 patients with moderate to severe gingivitis were selected for the study and divided into an experimental group (n = 5) and a control group (n = 5). The experimental group was given noni, and the control group was given chlorhexidine mouthwash as a pre-procedural rinse. Saliva samples were collected before and after the use of pre-procedural rinse from both the groups. The total colony-forming units were counted by inoculating nutrient agar by the pour plate method. Results: Noni (P = 0.039) as a pre-procedural rinse has statistically significant results compared to chlorhexidine (P = 0.061). Conclusion: The antibacterial effect of noni was seen to be effective in gingivitis patients.

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    Author(s) Name:

    Christeena Abraham*, M. Sankari

    Affiliation(s) Name:

    Department of Periodontics, Saveetha Dental College, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Christeena Abraham, Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India

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    Christeena Abraham*, M. Sankari

    Title:Effect of noni as a pre-procedural rinse in gingivitis patients: A cross-sectional study
    Journal:Drug Invention Today
    Vol(issue):10 (Sept [ Special Issue 1 ])
    Page No: (2663-2665)
  • Experimental Methods Keywords

    Methodology:A cross-sectional study
    Research Materials:10 patients, Morinda citrifolia


Chlorhexidine Gingivitis Morinda citrifolia Noni Pre-procedural rinse

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