Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002713
Title: In vitro evaluation of the antibacterial activity of ajwain oil on enteric pathogens
Category: Pharmacology
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    Introduction: Essential oils are recently explored for many of their therapeutic potentials, and ajwail oil is traditionally well known for its diverse therapeutic uses. Aim: The aim of the present study was to evaluate the in vitro antibacterial activity of ajwain oil on selected enteric pathogens. Materials and Method: Different concentrations of ajwain oil (40, 80, and 100 µl/mL) were tested for its antibacterial activity against Escherichia coli, Enterococcus Faecalis, and Klebsiella, using agar well diffusion technique using Mueller-Hinton agar. The zone of inhibition was measured to find the antibacterial activity of ajwain oil. Amikacin was used as the positive control. All the tests were done in triplicate to minimize the test error. Results: The study showed that ajwain oil exhibits antibacterial activity against the enteric pathogens in a dose-dependent manner, and the maximum activity was shown against E. coli with a zone of inhibition of 40 mm at the maximum dose used for the study. Conclusion: The antibacterial activity of ajwain oil against these microorganisms provides a scientific background for its use in infections caused by the tested organisms. The presence of thymol in the ajwain oil may be responsible for its antibacterial effect against E. coli, E. faecalis, and Klebsiella.

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    Author(s) Name:

    Nauma Hafeez 1 , Anitha Roy 1 *, R. V. Geetha2 , T. Lakshmi 1

    Affiliation(s) Name:

    1 Department of  Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University. Chennai, Tamil Nadu, India

    *Corresponding author: Dr. Anitha Roy, Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University. Chennai, Tamil Nadu, India

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    Author:

    Nauma Hafeez 1 , Anitha Roy 1 *, R. V. Geetha2 , T. Lakshmi 1

    Title:In vitro evaluation of the antibacterial activity of ajwain oil on enteric pathogens
    Journal:Drug Invention Today
    Vol(issue):10 (Sept [ Special Issue 1 ])
    Year:2018
    Page No: (2666-2668)
  • Experimental Methods Keywords

    Methodology:Agar well diffusion, Enteric pathogens,antibacterial activity
    Research Materials:Ajwain oil

Keywords

Agar well diffusion Ajwain oil Enteric pathogens Trachyspermum ammi

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