Journal: Drug Invention Today

Article Id: JPRS-D(DD)-00002733
Title: Targeted drug delivery systems used in dentistry - A short review
Category: Drug (Discovery/Development)
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    Targeted drug delivery is a specialized form of drug delivery which involves the controlled release of drugs in the desired location over a period of time. The main goal of target drug delivery system is to prolong, localize the target action to provide a protected drug interaction with the diseased tissues. The drug is delivered selectively to targeted areas of action or absorption and helps in preventing damage to non-targeted cells, tissues or organs. It provides a better method of drug delivery when compared to systemic dosage forms. These drugs are in the form of nanoparticles which are released in the target area, thereby avoiding interactions with healthy tissues. This can be achieved through means of active targeting or passive targeting in the region of diseased tissues. Drugs can be delivered through different vehicles such as polymeric micelles, liposomes, lipoprotein based drug carriers, nanoparticle drug carriers and dendrimers. These drug delivery systems have various applications including stem cell therapy, regenerative procedures and cancer treatments. In dentistry, the various drugs administered through this technique which is found to be beneficial in patients with gingivitis, periodontitis and other oral diseases. This study was done to assess the benefits of these target drug delivery systems to prevent discomfort or any other side effects for the patients and to analyze its scope in future dental practice. Hence, this review article aims at critically analyzing the different local drug delivery systems used in dentistry and analyze the indications, contraindications, benefits, and side effects of these systems for their effective use in patients.

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    Author(s) Name:

    Lakshmi Prabha J, Anitha Roy*, Lakshmi T

    Affiliation(s) Name:

    Department of Pharmacology ,Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. Anitha Roy, Associate Professor, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Velappanchavadi,Chennai - 600 077, Tamil Nadu, India.

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    Author:

    Lakshmi Prabha J, Anitha Roy*, Lakshmi T

    Title:Targeted drug delivery systems used in dentistry - A short review
    Journal:Drug Invention Today
    Vol(issue):10 (Sept [ Special Issue 1 ])
    Year:2018
    Page No: (2747-2751)
  • Experimental Methods Keywords

    Methodology:Targeted drug delivery
    Research Materials:Drugs

Keywords

Active targeting Delivery vehicles Drug delivery Passive targeting Target

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