Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002783
Title: Antibacterial activity of dry ginger against methicillin-resistant Staphylococcus aureus
Category: Pharmacology
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a Gram-positive, it is any strain of S. aureus that has developed, through horizontal gene transfer and natural selection, multiple drug resistance to beta-lactam antibiotics. It is a facultative anaerobe that can grow without the need for oxygen. Spread of S. aureus (including MRSA) generally is through human-to-human contact. The rise in antibiotic resistance has resulted in a decreasing number of fully active antimicrobial agents available to treat infections caused by multidrug-resistant bacteria that are the MRSA. The aim is to find out whether the dry ginger can suppress the activity of the MRSA. Materials and Methods: The extracts were prepared in different concentrations in sterile water, 5 mg/ml, 10 mg/ml, and 20 mg/ml. The screening of antibacterial activity of the dry ginger extract was carried out using the agar well diffusion method. Lawn culture of the test organism was made on the Muller-Hinton agar. A sterile cork borer was then used to make wells (6 mm diameter) for different concentrations of the extracts, 100 μl of the varying concentrations (500 µg/ml, 1000 µg/ml, and 2000 µg/ml) of the extracts were introduced into the wells with the help of micropipettes. The culture plates were incubated at 37°C for 24 h. After 24 h, antibacterial activity was determined by measurement of diameter of zones of inhibition (mm). Results: The investigation of antibacterial activity of dry ginger extract against, MRSA was done by agar well diffusion method. Mean zones of inhibition of different concentrations were measured and compared with the control. The extract showed good antibacterial activity at different concentrations with maximum zone of inhibition of 24 mm at concentration of 2000 µg/ml.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    S. P. Ashwin Kumar, R. V. Geetha*

    Affiliation(s) Name:

    1 Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author:R. V. Geetha, Department of Microbiology,Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    S. P. Ashwin Kumar, R. V. Geetha*

    Title:Antibacterial activity of dry ginger against methicillin-resistant Staphylococcus aureus
    Journal:Drug Invention Today
    Vol(issue):10 (October [ Special Issue 2 ])
    Year:2018
    Page No: (2930-2932)
  • Experimental Methods Keywords

    Methodology:Agar well diffusion assay,Methicillin-resistant Staphylococcus aureus, Zone of inhibition
    Research Materials:Dry ginger

Keywords

Agar well diffusion assay Dry ginger Methicillin-resistant Staphylococcus aureus Zone of inhibition

Our Services

Most Downloaded List