Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002785
Title: Microbiocenosis of the intestine of patients with exudative and hyperkinetic mechanisms of diarrhea
Category: Pharmacology
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Aim: A retrospective and prospective analysis of 63 outpatient cards of patients with organic (ulcerative colitis, Crohn’s disease, and intestinal polyposis) and functional (irritable bowel syndrome) lesions of the gastrointestinal tract was performed. Method: The basis for the selection of patients with gastroenterological pathology has been the mechanisms of the development of diarrhea. All patients underwent microbiological analysis of feces for dysbacteriosis. Results: The carried out researches allowed to conclude that the shifts in the intestinal microbiocenosis of the examined patients toward reducing obligatory flora and the activation of opportunistic pathogens, combined with genetically determined biological changes, lead to an increase in intestinal permeability and, as a consequence, the development of clinical manifestations of the disease. Conclusion: Thus, the analysis of our own studies of patients with organic and functional intestinal lesions as well as the results of various research groups indicates that a change in the intestinal microbiocenosis in the direction of declining obligatory flora and activation of opportunistic microorganisms, combined with genetically determined biological changes, leads to an increase in intestinal permeability and, as a consequence, the development of clinical manifestations of the disease with the development of dysbiotic shifts.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    Nurkiya Talgatbekova1 *, Nelya Bisenova2 , Kayergeldy Makhambetov1 , Elmira Kasenova1

    Affiliation(s) Name:

    1 Department of General Medicine, JSC “Astana Medical University,” Republic of Kazakhstan - 010 000, Astana,

    2 Laboratory of Microbiology, National Scientific Medical Center, Republic of Kazakhstan - 010 000, Astana

    *Corresponding author: Nurkiya Talgatbekova, Department of General Medicine, JSC “Astana Medical University,” Beybitshilik Street, 49a, Republic of Kazakhstan - 010 000, Astana.

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Nurkiya Talgatbekova1 *, Nelya Bisenova2 , Kayergeldy Makhambetov1 , Elmira Kasenova1

    Title:Microbiocenosis of the intestine of patients with exudative and hyperkinetic mechanisms of diarrhea
    Journal:Drug Invention Today
    Vol(issue):10 (October [ Special Issue 2 ])
    Year:2018
    Page No: (2937-2943)
  • Experimental Methods Keywords

    Methodology:Dysbacteriosis, Human microflora, Hyperkinetic mechanisms of diarrhea
    Research Materials:Diarrhea patients

Keywords

Dysbacteriosis Human microflora Hyperkinetic mechanisms of diarrhea

Our Services

Most Downloaded List