Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002793
Title: Risk for health of adolescents of the city of Kazan related to water consumption
Category: Pharmacology
Section: Research Article
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    Aim: We assessed the non-carcinogenic risk to the health of the adolescent population by oral intake of chemical compounds with drinking tap water on the basis of regional exposure factors. Materials and Method: The selection of study areas was carried out on the basis of the location of the permanent air pollution observation posts and the children’s polyclinics serving these areas (No. 1, 2, 3, 4) for the purpose of the subsequent complex assessment of multisided risk. Results: Results for non- carcinogenic risk assessment in delivery of chemicals to drinking water showed that the highest level of total hazard factor (HI = 7.5 and 3.5) was observed in Vakhitovsky zone (zone1) and Volga regions (zone 4). The main contribution to the risk 1 zone is made: Petroleum - 54%, nitrates (by NO3) - 12.8%, chloroform - 9.8%, fluorides - 6.4%, magnesium - 4.7%, and iron - 4.7% of the total risk. Runner risk level 4 occupies a zone where the main fraction is also determined risk value nitrite (for NO3) - 32%, oil, 29.7%, 13.2% chloroform, 9.1% chlorine fluorides - 5.6%. This trend is typical for other areas of the city: Chloroform, fluorides, nitrates, iron, and oil products which account for 67.4–73.1% of the total risk. Conclusion: The ranking by risk and the percentage distribution of the obtained data demonstrate that the main critical organs and systems are blood (12.1–28.2%), central nervous system (CNS) (10.09–10.6%), kidneys (3.5–23.07%), the endocrine system (7.0– 125%), cardiovascular (6.29–17.3%), bone system (6.6–7.3%), and teeth (2.7–6.4%).

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    Author(s) Name:

    Emilia R. Valeeva*, Gulgena A. Ismagilova, Alfiya I. Ziyatdinova, Rustem R. Sayfullin, Alisa R. Ilyasova

    Affiliation(s) Name:

    Department of Medicine, Institute of Fundamental Medicine and Biology, Kazan Federal University, 18 Kremlyovskaya St., 420 008 Kazan, Republic of Tatarstan, Russian Federation

    *Corresponding author: Emiliya R. Valeeva, Institute of Fundamental Medicine and Biology, Kazan Federal University, 18 Kremlyovskaya St., - 420 008 Kazan, Republic of Tatarstan, Russian Federation.

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    Author:

    Emilia R. Valeeva*, Gulgena A. Ismagilova, Alfiya I. Ziyatdinova, Rustem R. Sayfullin, Alisa R. Ilyasova

    Title:Risk for health of adolescents of the city of Kazan related to water consumption
    Journal:Drug Invention Today
    Vol(issue):10 (October [ Special Issue 2 ])
    Year:2018
    Page No: (2977-2980)
  • Experimental Methods Keywords

    Methodology:Non-carcinogenic risk, Target organs, Total health risk
    Research Materials:water consumption

Keywords

Adolescents Drinking water Non-carcinogenic risk Target organs Total health risk

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