Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002834
Title: Examining the risk factors of conversion to open surgery in patients with urgent laparoscopic cholecystectomy
Category: Pharmacology
Section: Research Article
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    Introduction: Laparoscopic cholecystectomy (LC) is the gold standard for treating gallbladder disease. However, approximately 2–15% of patients require conversion to open surgery for various reasons. In this study, we investigated predictive risk factors of conversion in patients undergoing LC for acute cholecystitis. Materials and Methods: We included 143 patients with acute cholecystitis who underwent LC from January 2010 to December 2014 in our Isesaki Municipal Hospital. A total of 15 patients needed conversion to open cholecystectomy (OC). Patients who completed LC and required conversion to OC were compared in terms of age, sex, body mass index, fever (>38°C), Murphy’s sign, laboratory and computed tomography (CT) findings, pre-operative endoscopic retrograde cholangiopancreatography, operation time and bleeding, and duration of hospital stay. Results: The overall conversion rate was 10.5%. Univariate analysis showed that age, sex, fever, Murphy’s sign, raised white blood cell, blood platelet, C-reactive protein, gallbladder wall thickness on CT, and operative bleeding were significantly correlated with conversion. Conclusions: It is possible to predict the risk of conversion. We should emphasize the possibility of conversion to those patients preoperatively.

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    Author(s) Name:

    Nobuhiro Nakazawa1 *, Hideki Suzuki 1 , Shigehumi Tanaka1 , Hiroyuki Kuwano2 , Ken Shirabe2

    Affiliation(s) Name:

    1Department of Surgery, Isesaki Municipal Hospital, 12-1, Tsunatorihonmachi, Isesaki, Gunma, Japan,

    2 Department of General Surgical Science, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, Japan

    *Corresponding author: Nobuhiro Nakazawa, Department of Surgery, Isesaki Municipal Hospital, 12-1, Tsunatorihonmachi, Isesaki, Gunma, Japan.

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    Author:

    Nobuhiro Nakazawa1 *, Hideki Suzuki 1 , Shigehumi Tanaka1 , Hiroyuki Kuwano2 , Ken Shirabe2

    Title:Examining the risk factors of conversion to open surgery in patients with urgent laparoscopic cholecystectomy
    Journal:Drug Invention Today
    Vol(issue):10 (November [ Special Issue 3 ])
    Year:2018
    Page No: (3166-0)
  • Experimental Methods Keywords

    Methodology: Acute cholecystitis, Conversion, Laparoscopic cholecystectomy, Risk factors
    Research Materials:143 patients with acute cholecystitis

Keywords

Acute cholecystitis Conversion Laparoscopic cholecystectomy Risk factors

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