Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002845
Title: Evaluation of antimicrobial activity of commercially available herbal toothpaste - An in vitro study
Category: Pharmacology
Section: Research Article
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    Introduction: The presence of Streptococcus mutans has been consistently linked with the etiology of many oral problems such as the dental caries due to their mechanisms of plaque biofilm development and accumulation of acids. As synthetic dentifrices commonly used contain chemical agents, which are known to produce harmful side effects on prolonged use. Several antimicrobial chemicals, incorporated into toothpaste, can be beneficial in the prevention of dental caries. Inhibition of each step in this process of caries formation contributes to the prevention of dental caries. Several medicinal plants have been recently found to have antimicrobial properties. Hence, the extracts of these plants have been used to improve dental health and oral hygiene. The aim of the study is to evaluate the antibacterial activity of herbal toothpaste on S. mutans level - an in vitro study. Materials and Methods: Eight commercially available herbal toothpastes were included in the study. Antimicrobial efficacies of dentifrices were tested by measuring the maximum zone of inhibition at 24 h on the Muller- Hilton agar media inoculated with microbial stain using disk diffusion method. Results: The study showed that herbal toothpaste containing clove was effective against S. mutans than the fluoridated toothpaste with a zone of inhibition of 22 mm. Conclusion: The antibacterial properties of eight dentifrices were studied in vitro and concluded that the use of herbal toothpaste may reduce the streptococcus count due to their antimicrobial activity and could help lower the prevalence of dental problems and maintain oral hygiene in the population.

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    Author(s) Name:

    H. Firdus Fareen1 , R. V. Geetha2 *

    Affiliation(s) Name:

    1Department of Microbiology, Saveetha Dental College and Hospital, Saveetha University, Chennai, Tamil Nadu, India,

    2Department of Microbiology, Saveetha Dental College and Hospital, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. R. V. Geetha, Department of Microbiology, Saveetha Dental College and Hospital, Saveetha University, 162, Poonamallee High Road, Velappanchavadi, Chennai - 600 095, Tamil Nadu, India.

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    Author:

    H. Firdus Fareen1 , R. V. Geetha2 *

    Title:Evaluation of antimicrobial activity of commercially available herbal toothpaste - An in vitro study
    Journal:Drug Invention Today
    Vol(issue):10 (November [ Special Issue 3 ])
    Year:2018
    Page No: (3214-3217)
  • Experimental Methods Keywords

    Methodology:Antimicrobial, Muller-Hilton agar, Plaque, Streptococcus mutans, Zone of inhibition
    Research Materials:Commercially available herbal toothpaste

Keywords

Antimicrobial Muller-Hilton agar Plaque Streptococcus mutans Zone of inhibition

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