Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002853
Title: Antibacterial effect of the crude extract of garlic on Streptococcus mutans
Category: Pharmacology
Section: Research Article
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    Introduction: Streptococcus mutans is one of the most common bacteria that are present in the saliva. It is a Gram-positive cocci, non-motile, either aerobic or facultative anaerobic microorganism that plays a major role in initiation of dental caries as they can metabolize carbohydrates. Garlic (Allium sativum) is a herb known for its antimicrobial effects as it has inhibitory activity on various pathogenic bacteria, viruses, and fungi. Its antibacterial activity depends on allicin produced by enzymatic activity of alliinase. Aim: This study was performed to analyze the antimicrobial effect of the crude extract of A. sativum - garlic (test group) against the S. mutans and compared the same with chlorhexidine (positive control group). Materials and Methods: The crude extract of garlic which was made into a paste was filled in the cavities made on the culture medium with strains of S. mutans and checked for the zone of inhibition. Zone of inhibition was also checked for chlorhexidine. Result: The crude extract of garlic showed a zone of inhibition against S. mutans but not as effective as chlorhexidine.

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    Author(s) Name:

    Radha Vellayappan*, Sheeja S. Varghese

    Affiliation(s) Name:

    Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, India

    *Corresponding author: Radha Vellayappan, Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, India

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    Author:

    Radha Vellayappan*, Sheeja S. Varghese

    Title:Antibacterial effect of the crude extract of garlic on Streptococcus mutans
    Journal:Drug Invention Today
    Vol(issue):10 (November [ Special Issue 3 ])
    Year:2018
    Page No: (3258-3261)
  • Experimental Methods Keywords

    Methodology: Antibacterial effects, Antibacterial property, Chlorhexidine, Garlic, Streptococcus mutans
    Research Materials: Allium sativum

Keywords

Allium sativum Antibacterial effects Antibacterial property Chlorhexidine Garlic Streptococcus mutans

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