Journal: JPR:BioMedRx:An International Journal

Article Id: JPRS-Pha-0000289
Title: Evaluation of Acute Toxicity for Solanum Xanthocarpum Fruits
Category: Pharmacology
Section: Research Article
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    The study was designed to evaluate the acute toxicity study of powder of fruits of Solanum Xanthocarpum. The fruits were collected from the basin of river Bhima during summer season in 2012 dried in shade to a constant weight and grinded by high power electric mixture and sieved. The acute toxicity study of fruit powder is carried out as per OECD guideline in Swiss mice weighing 35 to 50 gm. The dose of 2, 4, 6, 8 and 10 gm/kg body weight plant material were administered orally in the form of aqueous slurry. The groups were almost continuously observed for mortality and behavioral changes during first 24 hrs and then daily for fortnight. The observations of changes in body weight, food and water intake as well as cage side observations were reported during acclimatization as well as during study period. There was no abnormality observed in any group. The results provide evidence that Solanum Xanthocarpum fruits were found to be nontoxic in nature.

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  • About the authors and Affiliations

    Author(s) Name:

    Shirish S. Pingale

    Affiliation(s) Name:

    *P.G. Department of Chemistry, Gramonnati Mandal’s Arts, Com. & Sci. College,
    Narayangaon, Pune - 410 504 (Affiliated to University of Pune)

    *Corresponding author.
    Dr. Shirish S. Pingale
    Head, P.G. Department of Chemistry,
    Gramonnati Mandal’s Arts,
    Commerce and Science College, Narayangaon,
    Pune, Pin - 410 504, Maharashtra, India
    (Affiliated to University of Pune)


    Received on:14-01-2013; Revised on: 09-02-2013; Accepted on:26-02-2013

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    Author:

    Shirish S. Pingale

    Title:Evaluation of Acute Toxicity for Solanum Xanthocarpum Fruits
    Journal:JPR:BioMedRx:An International Journal
    Vol(issue):1 (March)
    Year:2013
    Page No: (330-332)
  • Experimental Methods Keywords

    Methodology:acute toxicity, acclimatization.
    Research Materials:Solanum Xanthocarpum

Keywords

Solanum Xanthocarpum acute toxicity acclimatization.

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