Journal: Drug Invention Today

Article Id: JPRS-Pcol-00002918
Title: Evaluation of qualitative, quantitative phytochemicals and in vitro antioxidant activities of methanolic leaf extract of Boerhaavia diffusa (Linn.)
Category: Pharmacology
Section: Research Article
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    Introduction: An oxidative stress result from the imbalance between the free radicals and enzymatic and non-enzymatic antioxidant systems. Boerhaavia diffusa (BD) (Linn.) is a well-known medicinal plant used in Indian traditional medicinal system. Objective: The objective of the present study was to find the qualitative, quantitative phytochemical and evaluate the in vitro antioxidant activity of methanolic leaf extract of BD (Linn.). Materials and Methods: The qualitative, quantitative phytochemical analysis and in vitro antioxidant activities such as 1-diphenyl-2-picrylhydrazyl (DPPH), hydrogen peroxide, superoxide hydroxy radical, and reducing power of methanolic leaf extract of BD (Linn.) were performed using established procedures. Results: The quantitative phytochemical analysis of the methanolic leaf extract of BD (Linn.) revealed that the presence of considerable amount of flavonoids, tannins, phenolic compounds, saponins, and alkaloids, and further, the in vitro antioxidant activity of methanolic leaf extract of BD (Linn.) showed significant scavenging activity on increasing order of H2 O2 (inhibitory concentration [IC50] value 178 µg/ml) DPPH (IC50 value 205 µg/ml) OH (197 µg/ml) and O2 (313 µg/ml) compared to that of standard ascorbic acid. Conclusion: It can be concluded that the methanolic leaf extract of BD (Linn.) has shown the significant in vitro antioxidant activity and it may be used as a potential source used as antioxidants to prevent oxidative stress-related diseases.

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    Author(s) Name:

    M. Muthulingam1 *, K. Krishna Chaithanya2

    Affiliation(s) Name:

    1 Department of Zoology, Faculty of Science, Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India,

    2 Departments of Chemistry, College of Natural and Computational Sciences, Aksum University, Aksum, Ethiopia

    *Corresponding author: Dr. M. Muthulingam, Department of Zoology, Annamalai University, Annamalai Nagar, Chidambaram - 608 002, Tamil Nadu, India.

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    Author:

    M. Muthulingam1 *, K. Krishna Chaithanya2

    Title:Evaluation of qualitative, quantitative phytochemicals and in vitro antioxidant activities of methanolic leaf extract of Boerhaavia diffusa (Linn.)
    Journal:Drug Invention Today
    Vol(issue):10 (December [ Special Issue 4 ])
    Year:2018
    Page No: (3565-3572)
  • Experimental Methods Keywords

    Methodology:Antioxidants,Inhibitory concentration, Qualitative phytochemical analysis, analysis
    Research Materials:Boerhaavia diffusa (Linn.)

Keywords

Antioxidants Boerhaavia diffusa (Linn.) Inhibitory concentration Qualitative phytochemical analysis analysis

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