Journal: Journal of Pharmacy Research

Article Id: JPRS-NTTM-00002961
Title: In vitro antioxidant and standardization studies on formulated hair oil AG2
Category: Natural Treatment of Traditional Medicine
Section: Research Article
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    Objective: The objective of the study was to develop herbal hair oil using leaves of Alternanthera sessilis L. and root powder of Glycyrrhiza glabra. Method: Preliminary phytochemical screening was performed for the herbal hair oil in the detection of secondary metabolites. The formulated oil was assessed by general physicochemical properties including color, odor, density, acid value, saponification value, peroxide value, and rancidity. In addition, gas chromatography-mass spectrometry (GC-MS) analysis was performed to identify the active metabolites in the formulation. In vitro antioxidant activity of prepared herbal hair oil was determined by (2, 2- Diphenyl-1-(2, 4, 6-trinitrophenyl) hydrazyl) radical scavenging assay. Results: GC-MS analysis detected 24 compounds from herbal formulation which exhibit various types of fatty acids, terpenoids and hydrocarbons. The major fatty acids found in the formulation were lauric acid (36.09%), myristic acid (19.97%), oleic acid (12.49%) and palmitic acid (11.81%). Antioxidant activity of formulated oil was determined and its IC50 value was found to be 50.84% at the concentration of 400µg/ml using gallic acid as standard. Conclusion: The result suggested that the selected herbs A. sessilis and G. glabra in coconut oil can contribute significantly in promoting hair growth. Chemical moieties identified might be contributing to the antioxidant efficacy of the developed herbal hair oil AG2.

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    Author(s) Name:

    Sudha Veerappan, Niraimathi Lakshmanan*, Lavanya Ramu, Brindha Pemaiah

    Affiliation(s) Name:

    Centre for Advanced Research in Indian System of Medicine (CARISM), SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India

    *Corresponding author: Niraimathi Lakshmanan, Centre for Advanced Research in Indian System of Medicine, SASTRA University, Thanjavur – 613 401, Tamil Nadu, India.

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    Author:

    Sudha Veerappan, Niraimathi Lakshmanan*, Lavanya Ramu, Brindha Pemaiah

    Title:In vitro antioxidant and standardization studies on formulated hair oil AG2
    Journal:Journal of Pharmacy Research
    Vol(issue):12 (March)
    Year:2018
    Page No: (431-435)
  • Experimental Methods Keywords

    Methodology:Antioxidant activity, gas chromatography-mass spectrometry, standardization
    Research Materials:hair oil

Keywords

Antioxidant activity gas chromatography-mass spectrometry hair oil standardization

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