Journal: Drug Invention Today

Article Id: JPRS-P col-00002986
Title: Pineal gland - A mystic gland
Category: Pharmaceutics
Section: Review Article
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    The pineal gland has been the subject of amazement and awe down the centuries. The structure and function of this enigmatic gland play an important role in day-to-day life of human beings. The pineal gland secretes an important hormone melatonin which is necessary for lightening the skin tone, and it has several other important functions in humans. The pineal gland is composed mainly of pinealocytes. The pineal gland is present in the midline of the skull and is a part of epithalamus and hypothalamus. It regulates the secretion of both. The pineal gland is activated by darkness and it is mandatory to maintain a normal circadian rhythm of sleep-wake cycle, if not humans may turn into zombies. The pineal gland is also present in animals. The secretion of this gland in higher amounts causes precocious puberty and development of primary and secondary sexual characters mainly in boys. It is also called the third eye since after eye, and it is the only gland which detects light but, on the contrary, secretes melatonin largely under darkness. This gland also affects the mood of human beings, thereby getting involved in the psychological behavior of men. It increases the immune action of human beings; thereby, it also acts as immunostimulant preventing a person from attack of antigen by producing a suitable antibody. Its presence hinders the spread of tumor and becomes malignant, and its calcification affects the memory or the memorizing capacity of the brain leading to dementia. This article reviews the anatomy and physiology of the pineal gland and the various functions of melatonin in humans.

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    Author(s) Name:

    Daniel Silas Samuel 1 , Revathi Duraisamy1 , M. P. Santhosh Kumar2 *

    Affiliation(s) Name:

    1 Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. M. P. Santhosh Kumar, Department of Oral and Maxillofacial Surgery, Saveetha Dental College,Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Velappanchavadi, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    Daniel Silas Samuel 1 , Revathi Duraisamy1 , M. P. Santhosh Kumar2 *

    Title:Pineal gland - A mystic gland
    Journal:Drug Invention Today
    Vol(issue):11 (January)
    Year:2019
    Page No: (55-58)
  • Experimental Methods Keywords

    Methodology:Mystic gland, Pineal gland, Sleep-wake cycle
    Research Materials:Melatonin

Keywords

Melatonin Mystic gland Pineal gland Sleep-wake cycle

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