Journal: Journal of Pharmacy Research
Title: Formulation and in vitro evaluation of niosome encapsulated acyclovir
Category: Pharmaceutics
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Acyclovir entrapped niosomes were prepared by hand shaking and ether injection process with different ratios of (1:1, 1;2 and 1:3) cholesterol (CHOL) and Span-80 (Non-ionic surfactant).The niosomes prepared were in the size range of 0.5- 5 microns in the case of hand shaking process and 0.5-2.5 microns in the case of Ether injection process. The order of encapsulation efficiency increases when span-80 concentration was increased. In-vitro release study on acyclovir niosomes indicates 76.64% release for formulation prepared with CHOL: Span-80 (1:1) and it takes an extended period of 1 day and 16 h for release.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Manivannan Rangasamy*, Balasubramaniam Ayyasamy,
Senthilkumar Raju1,Sandeep Gummadevelly2 and Sanaullah Shaik2
Affiliation(s) Name: 1Department of Pharm.Chemistry, Swamy Vivekanandha College of pharmacy, Elayampalayam, Namakkal, Tamilnadu, India.
2Department of Pharmaceutics, J.K.K.M.M.R.F, College of Pharmacy, B.Komarapalayam, Pin Code: 638 183, Namakkal, Tamilnadu, India.
For correspondence:
Manivannan Rangasamy, Dept.of Pharmaceutics, JKKMMRF’s college of Pharmacy, B.
Komarapalayam, Namakkal, Tamilnadu, India.
E-mail: manivannan_biotech@yahoo.co.in
Received on: 10-07-2008; Accepted on :02-10-2008-
View Article File in pdf format.
Article File
-
View Article Citation Here.
19 View More -
How to Cite my Article.
Author: Manivannan Rangasamy*, Balasubramaniam Ayyasamy,
Senthilkumar Raju1,Sandeep Gummadevelly2 and Sanaullah Shaik2
Title: Formulation and in vitro evaluation of niosome encapsulated acyclovir Journal: Journal of Pharmacy Research Vol(issue): 1 (Oct-December 2008) Year: 2008 Page No: (163-166) -
Experimental Methods Keywords
Methodology: Niosomes, Hand-Shaking process, Ether Injection process,VESICLE SIZE DETERMINATION Research Materials: Acyclovir
Keywords
Our Services
- Evaluation of Cardioprotective Role of Vinpocetine in Isoproterenol-induced Myocardial Infarction in Rats
- Solubility and Dissolution Enhancement: An overview
- Ethosomes: A novel tool for drug delivery through the skin
- A review on quality by design approach for analytical method development
- Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
- Evaluation of Phenolic Content and Antioxidant Capacity of leaf extract from Phoenix Dactylifera L obtained by different pH of aqueous extraction
- Benzoic acid, one of the major components of aqueous bark extract of Terminalia arjuna protects against Copper-Ascorbate induced oxidative stress in human placental mitochondria through antioxidant m
- Biological synthesis of silver nanoparticles using aqueous leaf extract of Capparis decidua (FORSK.) EDGEW: A better alternative
- Zinc-silibinin complex ameliorates oxidative stress in high fat fed low dose STZ induced type 2 diabetes in rats
- Study of health related quality of life in rheumatoid arthritis patients
- In vitro antioxidant, anti-inflammatory and anticholinesterase activities of Rumex vesicarius L
- Formulation and evaluation of topical gel of diclofenac sodium using different polymers
- Antimicrobial activity of seaweeds Gracillaria, Padina and Sargassum sps. on clinical and phytopathogensSubba Rangaiah G, Lakshmi P* and Manjula E
- Prescribing Patterns of antihypertensive drugs in a South Indian tertiary care hospital
- Gastroprotective effect of Fenugreek 4-hydroxyisoleucine and trigonelline enriched fraction (TF4H (28%)) Sugaheal® against indomethacin induced ulcer in male wistar rats.
- In vitro anti-Candida activity of Calotropis gigantea.
- Anti ulcer activity of Naravelia zeylanica leaves extract
- Melatonin affords protection against myocardial ischemia-induced cerebral mitochondrial dysfunction: an in vivo study.
- Pharmacognostic, Phytochemical & Quantitative Investigation of Saraca asoca leaves
- Synthesis and Biological Activity of Novel Acyl Hydrazone Derivatives of 3-(4,5-diphenyl-1,3-oxazol-2-yl) propanoic acid as Anticancer, Analgesic and Anti-inflammatory Agents
- Effects of Osmolytes on The Structural Stability of Bovine Trypsin: A Brief Review
- Design and Synthesis of Novel Quinazolinone Derivatives as Broad Spectrum Anticonvulsant and Antimicrobial Agent
- Genome of Acinetobacter baumannii Carries Multi Drug Resistance Genes
- In vitro Antioxidant Activity from Leaves of Oroxylum indicum (L.) Vent. -A North Indian Highly Threatened and Vulnerable Medicinal Plant
- Triazole analogues as novel antioxidants: In vitro bioassay and molecular modeling studies
- Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats
- In vitro antioxidant and ptp inhibitory activity of methanolic extract of Anogeissus acuminata leaf and bark.
- Assessment of Pharmacognostical Characters of Leaves of Tephrosia Purpurea Linn
- Anticonvulsant And Antioxidant Actions Of Some Dibenzo-a-Pyrone Derivatives In Pentylene –Induced Kindling Model In Mice
- Phytochemical Screening and Evaluation of Polyphenols, Flavonoids and Antioxidant Activity of Prunus cerasoides D. Don Leaves