Journal: Drug Invention Today

Article Id: JPRS-PDA-00003020
Title: In Vitro antioxidant activity of garden Croton (Codiaeum variegatum (L.) rumph. Ex A.Juss.) and phytochemical analysis using gas chromatography–mass spectrometry
Category: Pharmaceutical Drug Analysis
Section: Research Article
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    Introduction: Garden Croton (Codiaeum variegatum (L.) Rumph. ex A.Juss.) is an easily grown plant, has a various shape and colorful leaves which usually used as an ornamental plant. Objectives: The aims of the research were to determine the antioxidant activity of croton and its phytochemical content. The crude drug was extracted using 96% ethanol . Methods: Antioxidant activity was performed using DPPH free radical scavenging method and qualitative analysis was determined using GC‑MS. Results: Based on the in vitro antioxidant test using DPPH, IC50 of croton extract was 797.61 ppm while the IC50 of ascorbic acid was 8.97 ppm. Based on analysis of the chemical compound of croton using GC‑ MS, it obtained 10 compounds with percent of quality ( degree of similarity ) average > 90%. The main compounds were pentadecadien‑1‑ol 34.15% and hexadecanoic acid 21.14%. Conclusions: Croton leaves extract was categorized as low antioxidant activity and contained (6Z,9Z) pentadecadien‑1‑ol and hexadecanoic acid as the primary chemical content.

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    Author(s) Name:

    Siti Wanda Nurwanti*, R. E. Aritonang, Hefni Warnetty, R. S. Puspayani

    Affiliation(s) Name:

    Department of Pharmacy, Akademi Farmasi Hang Tuah, Jl. Farmasi No. 1 Bendungan Hilir, Jakarta Pusat, Indonesia

    *Corresponding author: Siti Wanda Nurwanti, Akademi Farmasi Hang Tuah Jakarta, Jl. Farmasi No. 1 Bendungan Hilir, Jakarta Pusat, 10210, Indonesia.

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    Author:

    Siti Wanda Nurwanti*, R. E. Aritonang, Hefni Warnetty, R. S. Puspayani

    Title:In Vitro antioxidant activity of garden Croton (Codiaeum variegatum (L.) rumph. Ex A.Juss.) and phytochemical analysis using gas chromatography–mass spectrometry
    Journal:Drug Invention Today
    Vol(issue):10 (December [ Special Issue 5 ])
    Year:2018
    Page No: (3781-3784)
  • Experimental Methods Keywords

    Methodology: Antioxidant, Gas chromatography–mass spectrometry
    Research Materials:Codiaeum Variegatum, Garden Croton

Keywords

Antioxidant Codiaeum Variegatum Garden Croton Gas chromatography–mass spectrometry

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