Journal: Drug Invention Today

Article Id: JPRS-P col-00003038
Title: The role of interleukin-1 in syndromes: Periodontal manifestation of systemic diseases
Category: Pharmacology
Section: Review Article
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    Periodontal disease is caused by dental plaque biofilms. Periodontitis is a common disease that causes tooth loss, and chronic inflammation induced by bacterial infection which is the major cause of periodontium destruction. The treatment for periodontitis depends on removal of periodontopathogens and their toxic products. Interleukin-1 (IL-1) is the prototypic pro-inflammatory cytokine. There are two kinds of IL-1, IL-1alpha and IL-1beta, and in most research, their biological sports are indistinguishable. IL-1 affects nearly every cell type, frequently inflammatory cytokine, tumor necrosis factor. Since IL-1 can upregulate host defenses and feature as an immunoadjuvant, IL-1 is a tremendously inflammatory cytokine. The objective of this review is to understand and provide information about the role of IL-1 in syndromes periodontal manifestation of periodontal diseases and update knowledge for further advancement in future. The aim of this review is to provide comprehensive information about the role of IL-1 in syndromes periodontal manifestation of systemic diseases and to understand the role of IL-1 in syndromes periodontal manifestation of systemic diseases.

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    Author(s) Name:

    D. Shruthi 1 , Caroline Annette Jacob1 , Antonette Rhea2

    Affiliation(s) Name:

    1 Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Antonette Rhea, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai – 600 077, Tamil Nadu, India.

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    Author:

    D. Shruthi 1 , Caroline Annette Jacob1 , Antonette Rhea2

    Title:The role of interleukin-1 in syndromes: Periodontal manifestation of systemic diseases
    Journal:Drug Invention Today
    Vol(issue):10 (December [ Special Issue 5 ])
    Year:2018
    Page No: (3862-3865)
  • Experimental Methods Keywords

    Methodology:Fibroblast, Integrin, Leukocyte, Prostaglandins
    Research Materials:Cytokines

Keywords

Cytokines Fibroblast Integrin Leukocyte Prostaglandins

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