Journal: Drug Invention Today

Article Id: JPRS-P col-00003044
Title: Ameliorative effect of hydroalcoholic extract of Caryota urens (Arecaceae) on streptozotocin-induced Alzheimer’s model in mice
Category: Pharmaceutics
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Alzheimer’s disease (AD) is a progressive brain disorder that gradually impairs memory and ability to learn, reasoning, judgment, communication, and daily activities. The present study is to evaluate the memory enhancement and cognitive effect of Caryota urens on Alzheimer’s induced mice using various memory retention experiments such as Y maze, Morris water maze, and Passive avoidance. In vitro evaluation of neurotransmitters was done on isolated brain tissue homogenates. AD was induced by intracerebroventricular injection of streptozotocin to mice. The selected dose 200 mg/kg and 400 mg/kg of C. urens showed significant action in memory and learning processes. From the results, it can be concluded that C. urens has promising effect in memory enhancement.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    P. Muralidharan1 , M. Prasanth1 , K. N. Jiji 1 *, S. Gejalakshmi 2

    Affiliation(s) Name:

    1 Department of Pharmacology, C. L. Baid Metha College of Pharmacy, Thoraipakkam, Chennai, Tamil Nadu, India,

    2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Dr. M. G. R. Educational and Research Institute, Velappanchavadi, Chennai, Tamil Nadu, India

    *Corresponding author: K. N. Jiji, Department of Pharmacology, C. L. Baid Metha College of Pharmacy, Thoraipakkam, Chennai, Tamil Nadu, India

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    P. Muralidharan1 , M. Prasanth1 , K. N. Jiji 1 *, S. Gejalakshmi 2

    Title:Ameliorative effect of hydroalcoholic extract of Caryota urens (Arecaceae) on streptozotocin-induced Alzheimer’s model in mice
    Journal:Drug Invention Today
    Vol(issue):11 (January)
    Year:2019
    Page No: (201-205)
  • Experimental Methods Keywords

    Methodology:Alzheimer’s disease, Cognitive effects
    Research Materials:Caryota urens (Arecaceae)

Keywords

Alzheimer’s disease Caryota urens Cognitive effects

Our Services

Most Downloaded List