Journal: JPR:BioMedRx:An International Journal

Article Id: JPRS-SDCS-0000307
Title: Free radical scavenging activity of essential oil compounds citral, limonene, menthone and thymol by using different methods
Category: Synthetic Drug Chemistry study
Section: Research Article
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    The essential oil compounds like Citral, Limonene, Menthone and Thymol was tested for a possible antioxidant activity. A rapid evaluation for antioxidants, using TLC screening methods, showed that Citral, Limonene, Menthone and Thymol demonstrated respectable radical scavenging property. These four constituents and the essential oil possessed variable antioxidant activity when tested in the diphenylpicrylhydracyl assay. All of the extracts had strong antioxidant activity in comparison to the standard compound curcumin. The antioxidant activities of the oils were evaluated in terms of their free-radical-scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH), Lipid Peroxidation, catalase and superoxide Dismutase. The antioxidant assays showed that the compounds possess very high radical scavenging activities DPPH IC(50) for thymol 1.2, limonene 24.8, citral 30.6 and menthone 79.6 µL/mL , Percentage reduction in Thiobarbituric acid reactive substances production (Lipid Peroxidation) for thymol 69.4, limonene 59.3, citral 52.1 and menthone 51.9 mg/mL, catalase production for thymol 43.8, limonene 42.6, menthone 41.3 and citral 40.2 mmol H2O2/min/mg of protein, superoxide production for thymol 434.8, limonene 404.4, menthone 372.2 and citral 372.1 Units /mg of protein. The results show that the essential oils possess significant antioxidant activity which is comparable to that of curcumin. These results suggest that the compounds citral, limonene, menthone and thymol act as a chemopreventative agent, providing antioxidant properties and offering effective protection from free radicals.

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    Author(s) Name:

    M. Vimal 1 *, P. P. Vijaya 2, P.Mumtaz 2, M.S.Seema Farhath 1

    Affiliation(s) Name:

    1Research Scholar,Department of Biotechnology,Bharathiar University,Coimbatore,Tamil Nadu, India .
    2Mohammed Sathak College of Arts and Science, Sholinganallur, Tamil Nadu, India .

    *Corresponding author.
    Vimal Manivannan
    Research Scholar,
    Department of Biotechnology,
    Bharathiar University,Coimbatore,
    Tamil Nadu, India


    Received on:11-01-2013; Revised on: 07-02-2013; Accepted on:25-03-2013

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    Author:

    M. Vimal 1 *, P. P. Vijaya 2, P.Mumtaz 2, M.S.Seema Farhath 1

    Title:Free radical scavenging activity of essential oil compounds citral, limonene, menthone and thymol by using different methods
    Journal:JPR:BioMedRx:An International Journal
    Vol(issue):1 (April)
    Year:2013
    Page No: (410-413)
  • Experimental Methods Keywords

    Methodology:Free radical scavenging activity,1,1-diphenyl-2-picrylhydrazyl (DPPH), Lipid Peroxidation, catalase and superoxide Dismutase
    Research Materials: Citral, Limonene, Menthone, Thymol

Keywords

Antioxidants Citral Limonene Menthone Thymol

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