Journal: Drug Invention Today

Article Id: JPRS-P col-00003114
Title: Analgesic efficacy of lornoxicam compared to paracetamol in the treatment of post-extraction pain
Category: Pharmaceutics
Section: Research Article
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    Aim and Objective: This study aims to compare the efficacy and rapidity of the action of lornoxicam and paracetamol in the management of post-extractive extraction pain. Background: Pain is a common experience following post-operative dental extractions. Post-operative dental pain may occur due to a non-isotonic solution, adrenaline in the solution, trauma, surgical interference, marked tissue destruction, acute inflammatory conditions, and infections. Many nonsteroidal anti-inflammatory drugs (NSAIDs) been in practice to manage the dental pain. Paracetamol and lornoxicam are also one of the most commonly used NSAIDs in dental practice. Materials and Methods: Patient seeking dental extraction without any periapical changes in the tooth was included in this study. The study consisted of 30 patients grouped into A and B with 15 in each group. The drug paracetamol and lornoxicam were given to 15 patients in Groups A and B, respectively, along with antibiotic (amoxicillin 500 mg) after extraction of the tooth. The patient was followed up for 3 consecutive days to review on pain. After extraction, patients were asked to score the pain range for 3 consecutive days in the form provided, while they are under the prescribed medications. Higher scores indicate worse, and lower scores indicate better efficacy of drug in post-extraction pain. Results: Patients under lornoxicam had less post-operative dental pain when compared to patient under paracetamol. Hence, lornoxicam proved to an effective analgesic for treating moderate-to-severe pain. Conclusion: Within the limitation of this study, it has been reported that lornoxicam has better efficiency in managing post-operative extraction pain and this will help the clinicians to treat the patients effectively and reduce their pain.

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    Author(s) Name:

    Harish Kumar Devarajan, 1 Sujatha Somasundaram2 *

    Affiliation(s) Name:

    1 Department of Paediatric and Preventive Dentistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Pedodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Sujatha Somasundaram, Department of Pedodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Science, Saveetha University, Chennai - 600 077, Tamil Nadu, India

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    Author:

    Harish Kumar Devarajan, 1 Sujatha Somasundaram2 *

    Title:Analgesic efficacy of lornoxicam compared to paracetamol in the treatment of post-extraction pain
    Journal:Drug Invention Today
    Vol(issue):12 (January)
    Year:2019
    Page No: (199-202)
  • Experimental Methods Keywords

    Methodology:Analgesics, Extraction, Post-operative pain
    Research Materials:Lornoxicam, Paracetamol

Keywords

Analgesics Extraction Lornoxicam Paracetamol Post-operative pain

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