Journal: Drug Invention Today

Article Id: JPRS-P col-00003146
Title: Bone morphogenic protein - 2 (BMP-2) and Osteogenesis
Category: Pharmaceutics
Section: Review Article
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  • Abstract

    Bone morphogenetic proteins (BMPs) are a family of potent, multifunctional growth factors belonging to transforming growth factor-β. BMPs can cause differentiation of bone marrow mesenchymal stem cells into osteoblastic lineage and promote the proliferation of osteoblasts. BMPs stimulate the target cells by specific membrane-bound receptors and signal transduced through mothers against and mitogen-activated protein kinase pathways. It has been demonstrated that play an important role in bone formation. This focuses on the molecular characterization of BMP-2 family and their application of oral and maxillofacial surgery. The role of BMP-2 has been studied extensively by Chandler in osteogenesis.

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    Author(s) Name:

    M. Indhumathi, Mimansa Bhoj*

    Affiliation(s) Name:

    Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha University, Chennai, Tamil Nadu, India,

    Corresponding author: Mimansa Bhoj, Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha University, Chennai, Tamil Nadu, India

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    Author:

    M. Indhumathi, Mimansa Bhoj*

    Title:Bone morphogenic protein - 2 (BMP-2) and Osteogenesis
    Journal:Drug Invention Today
    Vol(issue):11 (February)
    Year:2019
    Page No: (396-398)
  • Experimental Methods Keywords

    Methodology:A review
    Research Materials:BMP-2

Keywords

BMP-2 Osteoblasts target cells growth factor

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