Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-PSPA-0000319
Title: Studies on the hypoglycaemic activity of Acacia suma (Roxb.) barks.
Category: Phytochemical Study and Pharmacological Activity
Section: Research Article
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    The different extracts of the barks of Acacia suma (Roxb.) (Family-Fabaceae) was tested for hypoglycaemic activity in normoglycaemic and alloxan induced hyperglycaemic rats at dose levels of 100,200 and 400mg/kg, p.o. respectively. The extract was further subjected to oral glucose tolerance test in normal rats. The hypoglycaemic activity of the bark was compared with the reference standard glibenclamide (2.5 mg/kg, p.o.). The study revealed that the bark extract caused significant reduction in the blood glucose level in both normoglycaemic and alloxan induced diabetic rats at the tested dose levels in a dose dependant manner. In glucose-loaded animals, the extract also reduced the elevated blood glucose concentration. The study established the scientific basis for the utility of this plant in the treatment of diabetes and justifies the use of the barks of the plant for treating diabetes as suggested in folklore remedies.

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    Author(s) Name:

    Acharyya S.1*, Dash G. K.1, Mondal S.1, Acharyya A.1 and Dash S.K.2

    Affiliation(s) Name:

    1Matushree V. B. Manvar College of Pharmacy, Dumiyani, Rajkot dist., Gujarat -360 440.
    2P.G. department of Biosciences. College of Pharmaceutical Sciences, Mohuda, Berhampur
    Ganjam dist., Orissa-760002.

    *Corresponding author.
    Acharyya S
    Matushree V. B. Manvar College of Pharmacy,
    Dumiyani, Rajkot dist., Gujarat -360440. India


    Received on:10-09-2009; Revised on: 24-10-2009; Accepted on: 27-12-2009

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    Author:

    Acharyya S.1*, Dash G. K.1, Mondal S.1, Acharyya A.1 and Dash S.K.2

    Title:Studies on the hypoglycaemic activity of Acacia suma (Roxb.) barks.
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):1 (January )
    Year:2010
    Page No: (10-13)
  • Experimental Methods Keywords

    Methodology:hypoglycaemic activity, Glibenclamide, Hyperglycaemic, Normoglycaemic, Oral glucose tolerance Test (OGTT).
    Research Materials:Acacia suma

Keywords

Acacia suma Alloxan Glibenclamide Hyperglycaemic Normoglycaemic Oral glucose tolerance Test (OGTT).

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