Journal: Drug Invention Today

Article Id: JPRS-P col-00003225
Title: Toll-like receptors in periodontitis
Category: Pharmaceutics
Section: Review Article
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    Periodontitis is a chronic bacterial infection, stimulates the host inflammatory response through a sophisticated system based on toll-like receptors (TLRs) through a sophisticated system based on TLRs. Periodontitis is a chronic inflammatory condition in which TLRs play a major role in its pathogenesis. Recent research has indicated an essential role of these receptors in maintaining the periodontium in a healthy state, as well as in the causation of periodontitis. This review is focused on the latest findings of the TLRs family, its role TLRs and their signaling pathways, role in periodontitis, and therapeutics periodontitis.

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    Author(s) Name:

    P.  Jayamthi Govindaraj 1 *, Keerthidaa Govindaraj 2 , Kesavaram Padmavathi3 , Vidyarekha4 , Govindarajan Sumathy5

    Affiliation(s) Name:

    1 Department of Biochemistry, Sree Balaji Dental College and Hospital, Pallikaaranai, Chennai, Tamil Nadu, India,

    2 Department of Periodontics, Thai Mookambihai Dental College And Hospital, MGR University, Maduravoyal, Chennai, Tamil Nadu, India,

    3 Department of Microbiology, Sree Balaji Dental College and Hospital, Pallikaaranai, Chennai, Tamil Nadu, India,

    4 Department of Public Health Dentistry, Sree Balaji Dental College and Pallikaaranai, Chennai, Tamil Nadu, India,

    5 Department of Anatomy, Sree Balaji Dental College and Pallikaaranai, Chennai, Tamil Nadu, India

    *Corresponding author: P. Jayamthi Govindaraj, Department of Biochemistry, Sree Balaji Dental College and Hospital, Bharath Institute of Higher education and Research, Pallikaaranai, Chennai - 600100, Tamil Nadu, India.

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    Author:

    P.  Jayamthi Govindaraj 1 *, Keerthidaa Govindaraj 2 , Kesavaram Padmavathi3 , Vidyarekha4 , Govindarajan Sumathy5

    Title:Toll-like receptors in periodontitis
    Journal:Drug Invention Today
    Vol(issue):11 (March)
    Year:2019
    Page No: (630-633)
  • Experimental Methods Keywords

    Methodology:Periodontitis
    Research Materials:Toll-like receptors

Keywords

Drosophila Pathogen-associated molecular patterns Pro-inflammatory cytokines Toll-like receptors

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