Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-Es-0000325
Title: Advances in biochemical functions and the photochemistry of flavins and flavoproteins
Category: Enzyme study
Section: Review Article
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  • Abstract

    The biochemical and photochemical aspects of flavins and flavoproteins have been reviewed with particular reference to their biochemical functions, nutritional importance and photochemical reactions including photodegradation, photosensitization and photoreception. The flavin coenzymes are involved in a wide variety of metabolic reactions. The two main photochemical reactions of flavins have been described as intramolecular photoreduction and intramolecular photoaddition leading to the formation of lumichrome and cyclodehydroriboflavin, respectively, as the major final products. Flavin-sensitized photochemical reactions have important biological implications. The techniques of laser flash photolysis, femtosecond-resolved fluorescence spectroscopy and transient absorption spectroscopy have been applied to study the dynamics of flavoproteins. Information regarding the photostability of riboflavin (vitamin B2) in pharmaceutical preparations has been provided.

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    Author(s) Name:

    Iqbal Ahmad1*, Faiyaz H. M. Vaid2, Sofia Ahmed1, Muhammad Ali Sheraz1 and Sohail Hasan2

    Affiliation(s) Name:

    1* Institute of Pharmaceutical Sciences, Baqai Medical University, Toll Plaza, Super Highway, Gadap Road, Karachi-74600, Pakistan
    2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan

    *Corresponding author.
    Iqbal Ahmad
    Institute of Pharmaceutical Sciences,
    Baqai Medical University, Toll Plaza,
    Super Highway, Gadap Road,
    Karachi-74600, Pakistan


    Received on: 20-09-2009; Revised on: 06-12-2009; Accepted on:11-01-2010

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    Author:

    Iqbal Ahmad1*, Faiyaz H. M. Vaid2, Sofia Ahmed1, Muhammad Ali Sheraz1 and Sohail Hasan2

    Title:Advances in biochemical functions and the photochemistry of flavins and flavoproteins
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):1 (February)
    Year:2010
    Page No: (18-21)
  • Experimental Methods Keywords

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    Research Materials:Flavins, flavoproteins

Keywords

Flavins flavoproteins riboflavin biochemical functions photochemical reactions.

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