Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-PSPA-0000326
Title: Antihyperlipidemic potential of a polyherbal drug (Geriforte) on atherogenic diet induced hyperlipidemia: A Comparison with Ayurslim
Category: Phytochemical Study and Pharmacological Activity
Section: Research Article
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    We investigated the antihyperlipidemic activity of a polyherbal drug (Geriforte). The present study was undertaken to assess body weight, total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL) and very low density lipoprotein (VLDL) potential of the polyherbal drug (Geriforte) using atherogenic diet induced hyperlipidemia. The animals were divided into four groups: normal control, hyperlipidemic control, hyperlipidemic plus Geriforte and hyperlipidemic plus Ayurslim. Hyperlipidemia was induced by treated orally with butter fat (79% standard diet + 21% butter fat). Intragastric administration of Geriforte (450 mgkg-1 body weight) for 8 days significantly decreased body weight, TC, TG and LDL and VLDL whereas significantly increased level of HDL. Atherogenic index was lowered in the Geriforte drug fed animals when compared to hyperlipidemic animals. Geriforte exhibited quite competitive potential when compared with the reference drug Ayurslim affording a possible alternative therapeutic drug in the treatment of hyperlipidemia.

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    Author(s) Name:

    V. Maruthappana*, K. Sakthi Shreeb

    Affiliation(s) Name:

    a Unit of Endocrinology, Department of Zoology, Bharathiar University, Coimbatore – 641 046, India.
    b PG and Research Centre, Department of Zoology, Govt. Arts College (Autonomous), Coimbatore – 641 018, India.

    *Corresponding author.
    V. Maruthappan
    Unit of Endocrinology, Department of
    Zoology,Bharathiar University, Coimbatore, India.


    Received on: 23-10-2009; Revised on: 25-12-2009; Accepted on:18-02-2010

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    Author:

    V. Maruthappana*, K. Sakthi Shreeb

    Title:Antihyperlipidemic potential of a polyherbal drug (Geriforte) on atherogenic diet induced hyperlipidemia: A Comparison with Ayurslim
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):1 (March)
    Year:2010
    Page No: (37-39)
  • Experimental Methods Keywords

    Methodology:Antihyperlipidemic Activity
    Research Materials:Poly herbal drug

Keywords

Hyperlipidemia Geriforte Ayurslim Poly herbal drug.

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