Journal: Journal of Pharmacy Research
Title: Method development and its validation for simultaneous estimation of atorvastatin and amlodipine in combination in tablet dosage form by UV spectroscopy, using multi-component mode of analysis
Category: Pharmaceutics
Section: Research Article
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Abstract
Atorvastatin Calcium and Amlodipine Besilate in combination are available as tablet dosage forms in the ratio of 2:1. A simple, reproducible and efficient method for the simultaneous determination of Atorvastatin Calcium and Amlodipine Besilate in tablet dosage form has been developed. The developed method is based on the simultaneous estimation by UV Spectroscopy, using multi-component mode of analysis. 50%v/v aqueous methanol was used as blank. The validation studies were performed according to ICH guidelines.
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About the authors and Affiliations
Author(s) Name: V. Juyal1, M. Chaudhary1, P. Kumar1* ,G. Gnanarajan1, P. K. Yadav1
Affiliation(s) Name: 1 Deptt of Pharma Science SGRR ITS Patel Nagar, Dehradun 248001 (Uttra Khand),India
For correspondence:P.Kumar, Deptt of Pharma Science SGRR ITS Patel Nagar, Dehradun 248001(Uttra Khand),India
E-mail: praveen_mpharm_qa@yahoo.co.in
Received on: 08-05-2008; Accepted on :22-07-2008-
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Author: V. Juyal1, M. Chaudhary1, P. Kumar1* ,G. Gnanarajan1, P. K. Yadav1
Title: Method development and its validation for simultaneous estimation of atorvastatin and amlodipine in combination in tablet dosage form by UV spectroscopy, using multi-component mode of analysis Journal: Journal of Pharmacy Research Vol(issue): 1 (Oct-December 2008) Year: 2008 Page No: (182-187) -
Experimental Methods Keywords
Methodology: UV-Spectroscopy, Multicomponent mode of analysis, Research Materials: Atorvastatin Calcium and Amlodipine Besilate
Keywords
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