Journal: Journal of Pharmacy Research
Article Id: JPRS-PCS-000033
Title: Method development and its validation for simultaneous estimation of atorvastatin and amlodipine in combination in tablet dosage form by UV spectroscopy, using multi-component mode of analysis
Category: Pharmaceutics
Section: Research Article
Title: Method development and its validation for simultaneous estimation of atorvastatin and amlodipine in combination in tablet dosage form by UV spectroscopy, using multi-component mode of analysis
Category: Pharmaceutics
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Atorvastatin Calcium and Amlodipine Besilate in combination are available as tablet dosage forms in the ratio of 2:1. A simple, reproducible and efficient method for the simultaneous determination of Atorvastatin Calcium and Amlodipine Besilate in tablet dosage form has been developed. The developed method is based on the simultaneous estimation by UV Spectroscopy, using multi-component mode of analysis. 50%v/v aqueous methanol was used as blank. The validation studies were performed according to ICH guidelines.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: V. Juyal1, M. Chaudhary1, P. Kumar1* ,G. Gnanarajan1, P. K. Yadav1
Affiliation(s) Name: 1 Deptt of Pharma Science SGRR ITS Patel Nagar, Dehradun 248001 (Uttra Khand),India
For correspondence:P.Kumar, Deptt of Pharma Science SGRR ITS Patel Nagar, Dehradun 248001(Uttra Khand),India
E-mail: praveen_mpharm_qa@yahoo.co.in
Received on: 08-05-2008; Accepted on :22-07-2008-
View Article File in pdf format.
Article File
-
View Article Citation Here.
15 View More -
How to Cite my Article.
Author: V. Juyal1, M. Chaudhary1, P. Kumar1* ,G. Gnanarajan1, P. K. Yadav1
Title: Method development and its validation for simultaneous estimation of atorvastatin and amlodipine in combination in tablet dosage form by UV spectroscopy, using multi-component mode of analysis Journal: Journal of Pharmacy Research Vol(issue): 1 (Oct-December 2008) Year: 2008 Page No: (182-187) -
Experimental Methods Keywords
Methodology: UV-Spectroscopy, Multicomponent mode of analysis, Research Materials: Atorvastatin Calcium and Amlodipine Besilate
Keywords
UV-Spectroscopy
Multicomponent mode of analysis
Atorvastatin Calcium
Amlodipine Besilate
Validation
Authorised Login
Our Services
View
Most Downloaded List
- Evaluation of Cardioprotective Role of Vinpocetine in Isoproterenol-induced Myocardial Infarction in Rats
- Solubility and Dissolution Enhancement: An overview
- A review on Calotropis procera Linn and its Ethnobotany, Phytochemical, Pharmacological profile
- Ethosomes: A novel tool for drug delivery through the skin
- Antimicrobial activity and phytochemical screening of five wild plants against Escherichia coli, Bacillus subtilis and Staphylococcus aureus
- A review on quality by design approach for analytical method development
- Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
- Evaluation of Phenolic Content and Antioxidant Capacity of leaf extract from Phoenix Dactylifera L obtained by different pH of aqueous extraction
- Benzoic acid, one of the major components of aqueous bark extract of Terminalia arjuna protects against Copper-Ascorbate induced oxidative stress in human placental mitochondria through antioxidant m
- Zinc-silibinin complex ameliorates oxidative stress in high fat fed low dose STZ induced type 2 diabetes in rats
- Biological synthesis of silver nanoparticles using aqueous leaf extract of Capparis decidua (FORSK.) EDGEW: A better alternative
- Formulation and evaluation of topical gel of diclofenac sodium using different polymers
- Study of health related quality of life in rheumatoid arthritis patients
- In vitro antioxidant, anti-inflammatory and anticholinesterase activities of Rumex vesicarius L
- Antimicrobial activity of seaweeds Gracillaria, Padina and Sargassum sps. on clinical and phytopathogensSubba Rangaiah G, Lakshmi P* and Manjula E
- Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats
- Gastroprotective effect of Fenugreek 4-hydroxyisoleucine and trigonelline enriched fraction (TF4H (28%)) Sugaheal® against indomethacin induced ulcer in male wistar rats.
- Prescribing Patterns of antihypertensive drugs in a South Indian tertiary care hospital
- In vitro anti-Candida activity of Calotropis gigantea.
- Pharmacognostic, Phytochemical & Quantitative Investigation of Saraca asoca leaves
- Anti ulcer activity of Naravelia zeylanica leaves extract
- Melatonin affords protection against myocardial ischemia-induced cerebral mitochondrial dysfunction: an in vivo study.
- Synthesis and Biological Activity of Novel Acyl Hydrazone Derivatives of 3-(4,5-diphenyl-1,3-oxazol-2-yl) propanoic acid as Anticancer, Analgesic and Anti-inflammatory Agents
- Effects of Osmolytes on The Structural Stability of Bovine Trypsin: A Brief Review
- Design and Synthesis of Novel Quinazolinone Derivatives as Broad Spectrum Anticonvulsant and Antimicrobial Agent
- In vitro Antioxidant Activity from Leaves of Oroxylum indicum (L.) Vent. -A North Indian Highly Threatened and Vulnerable Medicinal Plant
- Genome of Acinetobacter baumannii Carries Multi Drug Resistance Genes
- Assessment of Pharmacognostical Characters of Leaves of Tephrosia Purpurea Linn
- Triazole analogues as novel antioxidants: In vitro bioassay and molecular modeling studies
- Anticonvulsant And Antioxidant Actions Of Some Dibenzo-a-Pyrone Derivatives In Pentylene –Induced Kindling Model In Mice