Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-000033
Title: Method development and its validation for simultaneous estimation of atorvastatin and amlodipine in combination in tablet dosage form by UV spectroscopy, using multi-component mode of analysis
Category: Pharmaceutics
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    Atorvastatin Calcium and Amlodipine Besilate in combination are available as tablet dosage forms in the ratio of 2:1. A simple, reproducible and efficient method for the simultaneous determination of Atorvastatin Calcium and Amlodipine Besilate in tablet dosage form has been developed. The developed method is based on the simultaneous estimation by UV Spectroscopy, using multi-component mode of analysis. 50%v/v aqueous methanol was used as blank. The validation studies were performed according to ICH guidelines.

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    Author(s) Name:

    V. Juyal1, M. Chaudhary1, P. Kumar1* ,G. Gnanarajan1, P. K. Yadav1

    Affiliation(s) Name:

    1 Deptt of Pharma Science SGRR ITS Patel Nagar, Dehradun 248001 (Uttra Khand),India


    For correspondence:P.Kumar, Deptt of Pharma Science SGRR ITS Patel Nagar, Dehradun 248001(Uttra Khand),India


    E-mail: praveen_mpharm_qa@yahoo.co.in


    Received on: 08-05-2008; Accepted on :22-07-2008

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    Author:

    V. Juyal1, M. Chaudhary1, P. Kumar1* ,G. Gnanarajan1, P. K. Yadav1

    Title:Method development and its validation for simultaneous estimation of atorvastatin and amlodipine in combination in tablet dosage form by UV spectroscopy, using multi-component mode of analysis
    Journal:Journal of Pharmacy Research
    Vol(issue):1 (Oct-December 2008)
    Year:2008
    Page No: (182-187)
  • Experimental Methods Keywords

    Methodology:UV-Spectroscopy, Multicomponent mode of analysis,
    Research Materials:Atorvastatin Calcium and Amlodipine Besilate

Keywords

UV-Spectroscopy Multicomponent mode of analysis Atorvastatin Calcium Amlodipine Besilate Validation

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