Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-AC-0000333
Title: Simultaneous estimation of aceclofenac, tramadol hydrochloride and paracetamol by UV spectrophotometric simultaneous equation method from tablet formulation
Category: Analytical Chemistry
Section: Research Article
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  • Abstract

    A simple, accurate, precise and economical procedure for simultaneous estimation of aceclofenac, tramadol hydrochloride and paracetamol in three component tablet dosage form has been developed utilizing concept of internal standard addition. The method is based upon determination of aceclofenac at 275.5nm, tramadol hydrochloride at 271.0 nm and paracetamol at 247.0 nm in methanol diluted with distilled water. Aceclofenac, tramadol hydrochloride and paracetamol at their respective ëmax 275.5nm, 271.0 nm and 247.0 nm shows linearity in the concentration range of 5- 25 μg/ml, 20-100 μg/ml and 3-15 μg/ml respectively. The method was validated statistically. Recovery study was performed to confirm the accuracy of the method.

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  • About the authors and Affiliations

    Author(s) Name:

    Deepali Gharge*, Pandurang Dhabale.

    Affiliation(s) Name:

    Government College of Pharmacy, Karad,Dist -Satara-415124, M.S., India.

    *Corresponding author.
    Deepali Gharge*
    Research Student,
    Government College of Pharmacy, Karad,
    Dist –Satara-415124, M.S., India.


    Received on: 10-11-2009; Revised on: 15-01-2010; Accepted on:08-02-2010

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    Author:

    Deepali Gharge*, Pandurang Dhabale.

    Title:Simultaneous estimation of aceclofenac, tramadol hydrochloride and paracetamol by UV spectrophotometric simultaneous equation method from tablet formulation
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):1 (March)
    Year:2010
    Page No: (58-61)
  • Experimental Methods Keywords

    Methodology:UV Spectrophotometric method
    Research Materials:Aceclofenac, Tramadol hydrochloride, Paracetamol

Keywords

Aceclofenac Tramadol hydrochloride Paracetamol Simultaneous equation method Recovery study.

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