Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-PSPA-0000340
Title: Evaluation of Antibacterial Activity of Lepidium sativum Linn. Seeds against Food-borne Pathogens
Category: Phytochemical Study and Pharmacological Activity
Section: Research Article
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    constituents of the dried powdered seeds were extracted using solvents viz., chloroform, ethyl acetate, methanol, and dichloromethane. The antibacterial activities of the concentrated extracts were evaluated by agar well diffusion method. The methanol extract showed the effective antibacterial activity against the pathogens used in this study. The minimum inhibitory concentrations (MIC) and minimum bactericidal concentration (MBC) were also determined for most active extract by tube dilution method and subculturing method respectively. The MIC values of the methanol extract ranged from 1.56 mg/ml to 25.0 mg/ml whereas the MBC values ranged from 6.25 mg/ml to 25.0 mg/ml. These results suggest the potential use of the seeds of Lepidium sativum for the control of infectious diseases from food poisoning. However, more adequate toxicological study must be carried out to verify the possibility of using it for fighting pathogenic microorganisms in human.

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    Author(s) Name:

    Prakash C. Gupta1*, Devki Pant1, P. Joshi1, D. R. Lohar1

    Affiliation(s) Name:

    1Homoeopathic Pharmacopoeia Laboratory, Kamala Nehru Nagar, Ghaziabad, 201001

    *Corresponding author.
    Prakash C. Gupta,
    Microbiology Laboratory, Homoeopathic Pharmacopoeia
    Laboratory, Department of AYUSH, Ghaziabad, 201001, India


    Received on: 26-11-2009; Revised on: 12-01-2010; Accepted on:19-03-2010

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    Author:

    Prakash C. Gupta1*, Devki Pant1, P. Joshi1, D. R. Lohar1

    Title:Evaluation of Antibacterial Activity of Lepidium sativum Linn. Seeds against Food-borne Pathogens
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):1 (April)
    Year:2010
    Page No: (74-75)
  • Experimental Methods Keywords

    Methodology:antibacterial activity, minimum inhibitory concentration, minimum bactericidal concentration, infectious disease.
    Research Materials:Lepidium sativum

Keywords

Lepidium sativum antibacterial activity minimum inhibitory concentration minimum bactericidal concentration infectious disease.

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