Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-PSPA-0000345
Title: Antibacterial Efficacy of Secondary Metabolites from Entomopathogenic Fungi Beauveria bassiana
Category: Phytochemical Study and Pharmacological Activity
Section: Research Article
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    This study was performed to evaluate the antibacterial activity of crude ethyl acetate extract of the entomopathogenic fungi Beauveria bassiana (ITCC 4688) against ten aerobic pathogenic bacteria including Bacillus megaterium, Staphylococcus aureus, Escherichia coli, Streptococcus pyogenes, Micrococcus luteus, Bacillus subtilis, Bacillus sphaericus, Klebsiella aerogenes, Psuedomonas aeruginosa and Chromobacterium violaceum. The acetate extracts of Beauveria bassiana (ITCC 4688) were shown to possess an inhibiting activity (MIC < or = mg/L) against many of the species tested. Significant antibacterial activity was found from 500 to 1000 μg/ml against Bacillus megaterium, Bacillus subtilis, Bacillus sphaericus, Escherichia coli; 700 to 1000 μg/ml against Micrococcus luteus, Pseudomonas aeruginosa and from 900 to 1000 μg /ml against Streptococcus pyogenes, Chromobacterium violaceum. The results suggest differential action of antibacterial property of crude extract of B. bassiana depending upon the active compounds on the specific bacteria. Hence, the present study gives an idea to test against more number of organisms and to find out the actual antibacterial compound from B. bassiana.

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    Author(s) Name:

    Narasimha Reddy Parine1, Akbar Ali Khan Pathan2, Sarayu B3, Veeturi Sudha Nishanth2, Varaprasad Bobbarala4*

    Affiliation(s) Name:

    1Centre for Cellular and Molecular Biology, Habsiguda, Hyderabad, India
    2Department of Biotechnology, GIT, GITAM University, Visakhapatnam, India
    3Enviromental Life Sciences, University of Salford, Greater Manchester, UK
    4Vivimed labs Limited, 2nd, 4th Floor, Veeranag towers, Habsiguda, Hyderabad, A.P.

    *Corresponding author.
    Dr. Varaprasad Bobbarala M.Sc., Ph.D.
    Head-Natural Products Chemistry
    Vivimed labs Limited,2nd, 4th Floor, Veeranag towers, Habsiguda, Hyderabad, A.P.


    Received on: 21-01-2010; Revised on: 18-03-2010; Accepted on:22-04-2010

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    Author:

    Narasimha Reddy Parine1, Akbar Ali Khan Pathan2, Sarayu B3, Veeturi Sudha Nishanth2, Varaprasad Bobbarala4*

    Title:Antibacterial Efficacy of Secondary Metabolites from Entomopathogenic Fungi Beauveria bassiana
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):1 (May)
    Year:2010
    Page No: (94-96)
  • Experimental Methods Keywords

    Methodology:antibacterial activity, MIC
    Research Materials:Beauveria bassiana

Keywords

Beauveria bassiana entomopathogenic fungi antibacterial activity MIC

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