Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-PC-0000347
Title: Combinatorial chemistry and its application - a review
Category: Pharmaceutical Chemistry
Section: Review Article
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  • Abstract

    The use of combinatorial chemistry techniques has been explored as an alternative to conventional approaches for the synthesis of compounds in the drug discovery process. This technique is the starting point for the development of synthesis concepts that were intended to cover and explore the chemical space without having to prepare every individual compound. Combinatorial Chemistry technologies were developed in response to the increased screening capacities that are available when drug discovery changed its screening paradigm from a pharmacology-based approach to target oriented lead finding. This article will illustrate technique used in combinatorial chemistry, some of the advances made in recent years and their application in the synthesis of different peptides, oligosaccharides and other molecules.

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  • About the authors and Affiliations

    Author(s) Name:

    AK Mishra1*, A Gupta1, AK Singh2, P Bansal3, S Kumar1, V Gupta1, BM Goyal1

    Affiliation(s) Name:

    1 National Institute of Ayurvedic Pharmaceutical Research, CCRAS, Patiala, India
    2 National Botanical Research Institute, Rana Pratap Marg, Lucknow, India
    3 Baba Farid University of Health Sciences, Faridkot, India

    *Corresponding author.
    AK Mishra
    National Institute of Ayurvedic Pharmaceutical Research, CCRAS, Patiala, India


    Received on: 20-01-2010; Revised on: 12-02-2010; Accepted on:19-04-2010

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    Author:

    AK Mishra1*, A Gupta1, AK Singh2, P Bansal3, S Kumar1, V Gupta1, BM Goyal1

    Title:Combinatorial chemistry and its application - a review
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):1 (May)
    Year:2010
    Page No: (100-105)
  • Experimental Methods Keywords

    Methodology:synthesis, solid phase, solution phase
    Research Materials:Combinatorial Chemistry,

Keywords

Combinatorial Chemistry synthesis solid phase solution phase

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