Journal: Drug Invention Today

Article Id: JPRS-P col-00003477
Title: In vitro antioxidant potential of stem of Amaranthus viridis - A medicine used in the Ayurvedic system of medicine
Category: Pharmaceutics
Section: Research Article
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    Aim: The study was aimed to assess the antioxidant potentials of Amaranthus viridis stem extract by 2, 2-Diphenyl-1- picrylhydrazyl (DPPH) radical, nitric oxide (NO) radical, and superoxide anion scavenging activity. Materials and Methods: A. viridis plant was collected from local market and stem was separated and shade dried. Aqueous extract of the stem of the plant was done as per the standard methods. Then, the antioxidant properties of A. viridis such as DPPH radical, NO anion, superoxide anion, and free radical-mediated DNA damage assays were analyzed spectrophotometrically by previously published methods. The data were analyzed using computer-based software by one- way Analysis Of Variance. In this, the significance is considered at the level of P < 0.05. Results: DPPH radical, NO radical, and superoxide anion radical scavenging activity was found to be increased in a dose-dependent manner. Conclusion: The present findings indicate that A. viridis can be used as a potential antioxidant for the treatment of various diseases.

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    Author(s) Name:

    Nadhirah Faiz1,V. Vishnu Priya1, R. Ponnulakshmi2, R. Gayathri1 , B. Shyamaladevi 1 , K. Madhan1 , M. Manikannan3 , J. Selvaraj1 *

    Affiliation(s) Name:

    1 Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India,

    2 Department of Central Research Laboratory, Meenakshi Academy of Higher Education and Research, Chennai, India,

    3 Centre for Drug Discovery and Development, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology, Chennai, India

    *Corresponding author: Dr. J. Selvaraj, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai - 600 077, India.

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    Author:

    Nadhirah Faiz1,V. Vishnu Priya1, R. Ponnulakshmi2, R. Gayathri1 , B. Shyamaladevi 1 , K. Madhan1 , M. Manikannan3 , J. Selvaraj1 *

    Title:In vitro antioxidant potential of stem of Amaranthus viridis - A medicine used in the Ayurvedic system of medicine
    Journal:Drug Invention Today
    Vol(issue):11 (May)
    Year:2019
    Page No: (1148-1151)
  • Experimental Methods Keywords

    Methodology: Antioxidant potential, Nitric oxide, Stem extract, Super oxide anion
    Research Materials:Amaranthus viridis

Keywords

2 2-Diphenyl-1-picrylhydrazyl Amaranthus viridis Antioxidant potential Nitric oxide Stem extract Super oxide anion

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