Journal: Drug Invention Today

Article Id: JPRS-P col-00003478
Title: Anti-inflammatory activity of Punica granatum peel extract – An in vitro analysis
Category: Pharmaceutics
Section: Research Article
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  • Abstract

    Aim: The aim of this study was to evaluate the anti-inflammatory activity of Punica granatum peel extract by in vitro analysis. Objective: The purpose of the study is to evaluate the anti-inflammatory activity of P. granatum peel extract by in vitro analysis. Materials and Methods: P. granatum was collected from local market, shade dried, and peeled. The ethanol extraction of P. granatum peel powder was done as per the standard method. Different concentrations of the extract were used for anti-inflammatory activity by inhibition of albumin denaturation and proteinase inhibitory action methods. All samples were analyzed in triplicate. The results were statistically analyzed. Results: The results indicate that the methanol extracts of P. granatum possess anti-inflammatory properties. Conclusion: It is concluded from the present study that methanol extracts of P. granatum possess anti-inflammatory properties due to the strong occurrence of polyphenolic compounds such as alkaloids, flavonoids, tannins, steroids, and phenols in the plant extracts.

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    Author(s) Name:

     Fathima  Bareera Rezvi 1 , V. Vishnu Priya1 , R. Ponnulakshmi 2 , R. Gayathri 1 , B. Shyamaladevi 1 , K. Madhan1 , M. Manikannan3 , J. Selvaraj1 *

    Affiliation(s) Name:

    1 Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Central Research Laboratory, Meenakshi Academy of Higher Education and Research, Chennai, Tamil Nadu, India,

    3 Centre for Drug Discovery and Development, Col. Dr. Jeppiaar Research Park, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. J. Selvaraj, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, 162, Poonamallee High Road, Chennai - 600 077, Tamil Nadu, India.

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    Author:

     Fathima  Bareera Rezvi 1 , V. Vishnu Priya1 , R. Ponnulakshmi 2 , R. Gayathri 1 , B. Shyamaladevi 1 , K. Madhan1 , M. Manikannan3 , J. Selvaraj1 *

    Title:Anti-inflammatory activity of Punica granatum peel extract – An in vitro analysis
    Journal:Drug Invention Today
    Vol(issue):11 (May)
    Year:2019
    Page No: (1152-1154)
  • Experimental Methods Keywords

    Methodology:Anti-inflammatory, Albumin denaturation
    Research Materials:Punica granatum

Keywords

Anti-inflammatory Punica granatum Plant extracts Albumin denaturation

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