Journal: Drug Invention Today

Article Id: JPRS-P col-00003526
Title: Estimation of salivary superoxide dismutase levels in chronic periodontitis patients with or without coronary heart disease
Category: Pharmacology
Section: Research Article
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    Background: Chronic periodontitis (CP) is an infectious disease which is caused by Gram-negative bacteria, which settles in the subgingival biofilm and leads to the destruction of the soft and hard tissues around the teeth. Aim: The aim of the study was to determine the levels of salivary superoxide dismutase (SOD) levels in CP level. Materials and Methods: The present study was conducted on subjects reporting to the Department of Periodontology at a Saveetha Dental College and Hospitals, SIMATS, Chennai, India. A sample of 15 was determined as the minimum in each group to estimate and to calculate for the statistical analysis. Results: Lower levels of antioxidants in diseased states of CP and coronary heart disease (CHD) point toward the conclusion that the disease process is a result of a balance tipped in favor of the oxidants, with failure of antioxidants to balance the oxidant levels. Conclusion: It is concluded that SOD levels in the saliva are proportionately decreased in CP with CHD and hence salivary SOD levels can be a biomarker for the CP+CHD as a non-invasive method.

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    Author(s) Name:

    Arunn Jaikumarr Ram1 , V. Vishnupriya1 , R. Ponnulakshmi 2 , R. Gayathri 1 , K. Madhan1 , B. Shyamaladevi 1 , J. Selvaraj1 *

    Affiliation(s) Name:

    1 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Central Research Laboratory, Meenakshi Academy of Higher Education and Research, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. J. Selvaraj, Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    Arunn Jaikumarr Ram1 , V. Vishnupriya1 , R. Ponnulakshmi 2 , R. Gayathri 1 , K. Madhan1 , B. Shyamaladevi 1 , J. Selvaraj1 *

    Title:Estimation of salivary superoxide dismutase levels in chronic periodontitis patients with or without coronary heart disease
    Journal:Drug Invention Today
    Vol(issue):12 (May)
    Year:2019
    Page No: (914-916)
  • Experimental Methods Keywords

    Methodology:Chronic periodontitis, Coronary heart disease, Salivary superoxide dismutase
    Research Materials:Chronic periodontitis patients

Keywords

Chronic periodontitis Coronary heart disease Salivary superoxide dismutase

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