Journal: Drug Invention Today

Article Id: JPRS-P col-00003528
Title: Effect of silver nanoparticles synthesized from Morinda citrifolia and irrigants against Streptococcus mutans biofilm
Category: Pharmacology
Section: Research Article
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    Background: Morinda citrifolia is a fruit-bearing tree in the coffee family, Rubiaceae. Silver nanoparticles (AgNPs) are used as carriers for delivering various payloads to specific targets. AgNPs showed more inhibitory actions against human pathogens than crude plant extract; this shows the antimicrobial value against pathogenic diseases. Aim: The study was aimed at assessing the antimicrobial activity of M. citrifolia coated AgNPs against Streptococcus mutans species. Materials and Methods: S. mutans biofilm formation: S. mutans UA159 was cultured in brain heart infusion medium in a favorable condition to form a biofilm and they were cultured aerobically at 37°C for 2 days for colony-forming unit counting. Minimum inhibitory concentration of M. citrifolia extract was examined against S. mutans. Inhibition potential of the extract on preformed biofilm was analyzed. Results: The AgNPs coated with M. citrifolia extract showed the greatest inhibition effect at high concentration. The inhibitory activity increases with increase in concentration of the extract. Conclusion: The AgNPs had a comparatively good inhibitory power, even though ciprofloxacin had higher inhibition, M. citrifolia coated NPs can be used because they are naturally synthesized and does not have any side effects.

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    Author(s) Name:

    Vasishta Pala1 , V. Vishnupriya1 *, J. Selvaraj 1 , R. Ponnulakshmi 2 , R. Gayathri 1 , K. Madhan1 , B. Shyamaladevi 1

    Affiliation(s) Name:

    1 Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Central Research Laboratory, Meenakshi Academy of Higher Education and Research, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. V. Vishnupriya, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    Vasishta Pala1 , V. Vishnupriya1 *, J. Selvaraj 1 , R. Ponnulakshmi 2 , R. Gayathri 1 , K. Madhan1 , B. Shyamaladevi 1

    Title:Effect of silver nanoparticles synthesized from Morinda citrifolia and irrigants against Streptococcus mutans biofilm
    Journal:Drug Invention Today
    Vol(issue):12 (May)
    Year:2019
    Page No: (920-922)
  • Experimental Methods Keywords

    Methodology:Silver nanoparticles
    Research Materials: Morinda citrifolia

Keywords

Morinda citrifolia Silver nanoparticles Streptococcus mutans

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