Journal: Drug Invention Today

Article Id: JPRS-P col-00003603
Title: Insulin-like growth factor-1 as a biochemical indicator for skeletal maturity: A literature review
Category: Pharmaceutics
Section: Review Article
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    Purpose: To assess the reliability of IGF-1 as a diagnostic biomarker for skeletal maturity using a collective data. Data identification: An English language literature search using PUBMED(2000-2018),HAND-PICKED JOURNALS, and bibliographic review of textbooks and articles. Study selection: After independent review by three observers, 17 of 700 originally identified articles were selected that specifically addressed the stated purpose. Results of data synthesis: The accumulated Randomized control trials suggested that IGF-1 as a skeletal maturity indicator has several advantages over other methods that has evolved from the chronological age, height, weight, dental eruption and calcification cycle, sexual maturation, sinus maturation, hand-wrist radiographs, cervical maturation and sutural maturation. Conclusion: The reliability of IGF-1 as a skeletal maturity indicator is well established.

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    Author(s) Name:

    Rashika Premkumar, Sanjay Sundararajan, Uma Maheshwari, Devaki Vijayalakshmi*

    Affiliation(s) Name:

    Department of Orthodontics, Faculty of Dentistry, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India

    *Corresponding author: Devaki Vijayalakshmi, Department of Orthodontics, Faculty of Dentistry, Meenakshi Ammal Dental College and Hospital, Alapakkam Main Road, Maduravoyal, Chennai - 600 097, Tamil Nadu, India.

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    Author:

    Rashika Premkumar, Sanjay Sundararajan, Uma Maheshwari, Devaki Vijayalakshmi*

    Title:Insulin-like growth factor-1 as a biochemical indicator for skeletal maturity: A literature review
    Journal:Drug Invention Today
    Vol(issue):11 (June )
    Year:2019
    Page No: (1382-1386)
  • Experimental Methods Keywords

    Methodology: skeletal maturity,biochemical indicator
    Research Materials:Insulin-like growth factor-1

Keywords

skeletal maturity IGF-1 biomarker

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