Journal: Drug Invention Today

Article Id: JPRS-P col-00003624
Title: Alpha-glucosidase inhibitory and lipase inhibitory activities of Sargassum wightii
Category: Pharmaceutics
Section: Research Article
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    Introduction: Lifestyle-related diseases such as diabetes are steadily increasing worldwide. Sargassum wightii (brown algae), algal polysaccharides, attracted extensive interest to study their numerous biological activities. Therefore, in the current study, the alpha-glucosidase inhibitory and pancreatic lipase inhibitory activities of methanolic extract will be investigated using in vitro assays. Aim: This research is to study the α-glucosidase inhibitory and lipase inhibitory activities of S. wightii. Materials and Methods: The alpha-glucosidase and pancreatic lipase inhibitory activity of S. wightii was assayed using Acarbose and Orlistat as positive control. Results: S. wightii has both alpha-glucosidase inhibitory and lipase inhibitory activity. Conclusion: S. wightii can be used as an alternative with further research as it is a plant extract.

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    Author(s) Name:

    I. Swetha1 , V. Vishnupriya2 , R. Gayathri 2 *

    Affiliation(s) Name:

    1 Department of Biochemistry, Saveetha Dental College,Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: V. Vishnu Priya, Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

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    Author:

    I. Swetha1 , V. Vishnupriya2 , R. Gayathri 2 *

    Title:Alpha-glucosidase inhibitory and lipase inhibitory activities of Sargassum wightii
    Journal:Drug Invention Today
    Vol(issue):11 (June )
    Year:2019
    Page No: (1471-1474)
  • Experimental Methods Keywords

    Methodology:Alpha-glucosidase inhibitory, lipase inhibitory activities
    Research Materials:Sargassum wightii

Keywords

Alpha-glucosidase Brown algae Pancreatic lipase Sargassum wightii

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