Journal: Drug Invention Today
Title: Cytotoxic evaluation of onion oil on oral cancer cell
Category: Pharmaceutics
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Aim: This research work was done to evaluate the anticancer potential of onion oil on oral cancer cell lines. Introduction: Onion (Allium cepa) herbaceous biennial plant belongs to the family Amaryllidaceae is grown for its edible bulb. Onion oil has flavoring properties that could enhance the quality of treated food. It has also been reported to have antioxidant, anti-browning, and antimicrobial properties Oral cancer is one of the most common malignancies in the world.The loss of regulation in cell division is the hallmark of all cancers. Materials and Methods: Onion oil was purchased commercially. The cytotoxicity of onion oil was studied by checking the cell viability using 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay (MTT assay) in KB cell lines. Results and Discussion: Onion oil decreased the cell viability in KB cell lines. The activity increases with increase in concentration of onion oil revealing its cytotoxicity in a concentration- dependent manner. Conclusion: This study established the potent in vitro cytotoxic effect of onion oil on oral cancer cell lines.
-
Abstract Audio
No Audio file found
About the authors and Affiliations
Author(s) Name: A. Aksha Sharen1 , S. Kavitha2 *, V. Vishnupriya2 , R. Gayathri 2
Affiliation(s) Name: 1 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,
2 Department of Biochemistry, Saveetha Dental College, Saveetha University, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
*Corresponding author: S. Kavitha, Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 160, Poonamallee High Road, Chennai - 600 077, Tamil Nadu, India.
-
View Article File in pdf format.
Article File
-
View Article Citation Here.
0 View More -
How to Cite my Article.
Author: A. Aksha Sharen1 , S. Kavitha2 *, V. Vishnupriya2 , R. Gayathri 2
Title: Cytotoxic evaluation of onion oil on oral cancer cell Journal: Drug Invention Today Vol(issue): 12 (July) Year: 2019 Page No: (1385-1387) -
Experimental Methods Keywords
Methodology: Cytotoxicity, KB cell lines, 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay Research Materials: onion oil
Keywords
Our Services
- Correlation of facial and nasal index in gender determination
- Morphometric analysis of gonial angle and mandibular ramus measurement as predictors of sex and age in dry human mandibles
- Medicinal uses of banana (Musa paradisiaca)
- Abutment selection in fixed partial denture - A review
- Craniometric analysis of foramen magnum with reference to occipital condyles for the determination of sex using dry human skulls
- Morphological and morphometrical analysis of Chassaignac’s tubercle in dry human cervical vertebrae
- Studies on antioxidant and anthelmintic activity of two Streptomyces species isolated from Western Ghat soils of Agumbe, Karnataka
- Benzoic acid, one of the major components of aqueous bark extract of Terminalia arjuna protects against Copper-Ascorbate induced oxidative stress in human placental mitochondria through antioxidant m
- Evaluation of phytochemical and pharmacological aspects of Holarrhena antidysenterica (Wall.): A comprehensive review
- Review On: Fast Dissolving Tablet
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Knowledge, attitude, and practices toward oral hygiene maintenance among patients visiting a dental college
- Prevalence pattern of developmental anomalies of oral cavity in South Indian population - A hospital-based study
- Self micro-emulsifying drug delivery system (SMEDDS) : Review
- Awareness about oral cancer among tobacco users visiting a private dental hospital in Chennai
- Thiophene: The molecule of diverse medicinal importance
- QbD Approach for Analytical Method Development and Validation of Melatonin by spectroscopic Method
- Knowledge and awareness among undergraduate dental students regarding oral health of diabetes mellitus patients
- Evaluating the effects of video games on blood pressure and heart rate
- Awareness and knowledge about usage of e-cigarettes and risk of cardiovascular disease among smokers
- Anticancer activity of L-theanine in MG-63 cell line
- Combinatory effect of embelin with antibiotics against Staphylococcus aureus
- Pharmaceutical and medicinal applications of Olibanum gum and its constituents : A review
- In vitro anti-Candida activity of Calotropis gigantea.
- A study of the factors affecting time to onset of lactogenesis-II after parturition
- Awareness of anemia among dental undergraduate students: A questionnaire-based study
- Impurity profile- A review
- Antihypertensive activity of ethanolic extract of Acacia nilotica
- Assessment of clinical skills of students in fixed partial denture
- Awareness on soil pollution among school students