Journal: Drug Invention Today
Title: Cytotoxic evaluation of onion oil on oral cancer cell
Category: Pharmaceutics
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Aim: This research work was done to evaluate the anticancer potential of onion oil on oral cancer cell lines. Introduction: Onion (Allium cepa) herbaceous biennial plant belongs to the family Amaryllidaceae is grown for its edible bulb. Onion oil has flavoring properties that could enhance the quality of treated food. It has also been reported to have antioxidant, anti-browning, and antimicrobial properties Oral cancer is one of the most common malignancies in the world.The loss of regulation in cell division is the hallmark of all cancers. Materials and Methods: Onion oil was purchased commercially. The cytotoxicity of onion oil was studied by checking the cell viability using 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay (MTT assay) in KB cell lines. Results and Discussion: Onion oil decreased the cell viability in KB cell lines. The activity increases with increase in concentration of onion oil revealing its cytotoxicity in a concentration- dependent manner. Conclusion: This study established the potent in vitro cytotoxic effect of onion oil on oral cancer cell lines.
-
Abstract Audio
No Audio file found
About the authors and Affiliations
Author(s) Name: A. Aksha Sharen1 , S. Kavitha2 *, V. Vishnupriya2 , R. Gayathri 2
Affiliation(s) Name: 1 Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,
2 Department of Biochemistry, Saveetha Dental College, Saveetha University, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India
*Corresponding author: S. Kavitha, Department of Biochemistry, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 160, Poonamallee High Road, Chennai - 600 077, Tamil Nadu, India.
-
View Article File in pdf format.
Article File
-
View Article Citation Here.
0 View More -
How to Cite my Article.
Author: A. Aksha Sharen1 , S. Kavitha2 *, V. Vishnupriya2 , R. Gayathri 2
Title: Cytotoxic evaluation of onion oil on oral cancer cell Journal: Drug Invention Today Vol(issue): 12 (July) Year: 2019 Page No: (1385-1387) -
Experimental Methods Keywords
Methodology: Cytotoxicity, KB cell lines, 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay Research Materials: onion oil
Keywords
Our Services
- Review On: Fast Dissolving Tablet
- Academic stress and its effect on medical students’ mental health status
- Awareness on influences of social media among children
- Citric acid production from cane molasses using submerged fermentation by Aspergillus niger ATCC9142
- Awareness on the effects of caffeine among students - A survey
- Complications of diabetes mellitus: A review
- Awareness on soil pollution among school students
- Impact of poultry consumption by adolescent females – An analytical study
- Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats
- Abrus precatorius Linnaeus: A Phytopharmacological Review
- Application of nanotechnology for Ayurvedic drugs and formulations
- Sleep deprivation and cell phone usage among teenagers
- Knowledge, perception, and awareness of text neck syndrome among young adults South Indian population
- Current Trends in Herbal Medicines
- Multiple-Unit-Pellet System (MUPS): A Novel Approach for Drug Delivery
- Physical signs of child abuse
- Estimation of E-guggulsterone, Z-guggulsterone and myrcene in Mahayograj Guggul tablet by high- performance thin-layer chromatography (HPTLC) method: A marketed herbal formulation
- Prevalence and pattern of use of complementary and alternative medicine in diabetes patients in a south Indian tertiary care teaching hospital
- impurities of sulphid drug substances
- Pharmacognostic Study Of Plant Euphorbia hirta L
- Annona squamosa L.:Phytochemical analysis and Antimicrobial Screening
- Chromolaena odorata (L.) : An Overview
- Physiological changes in pregnancy
- Awareness of selfie addiction among teenagers: A questionnaire-based study
- A review on various treatment modalities for oral lichen planus
- Development of promising fast dissolving tablets of Stiripentol: a novel antiepileptic drug
- Urease inhibitory activities of silver nanoparticles of Andrographis echioides fruit extract against Helicobacter pylori
- A study to assess the level of knowledge and level of anxiety on coronavirus disease 2019 among adults living in Adukkamparai
- Formulation and evaluation of buccoadhesive tablets of Atenolol
- Formulation of bilayer tablet containing metoprolol succinate and amlodipine besylate as a model drug for antihypertensive therapy