Journal: Drug Invention Today

Article Id: JPRS-P col-00003793
Title: Melatonin in periodontitis
Category: Pharmaceutics
Section: Review Article
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  • Abstract

    The concept of periodontal diseases as localized entities affecting only the teeth and supporting apparatus has been revised in the past few decades with considerable research focused on the wide-ranging systemic effects of these diseases. One of the mechanisms through which systemic health is affected in patients with periodontitis is through generation of reactive oxygen species and oxidative stress which induce a great deal of damage to various body tissues. To address this aspect, the use of antioxidants has become a standard part of medicinal treatment. Melatonin, an endogenous hormone produced by the pineal gland is a powerful antioxidant and possesses a number of other potentially beneficial biologic activities to prevent the damage produced by oxidative stress on periodontium and other organ systems. Current review article provides contemporary evidence for the role of melatonin in periodontal diseases and envisions at the emerging status of melatonin to be utilized as diagnostic, risk reduction, and therapeutic strategies in the field of periodontal medicine.

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  • About the authors and Affiliations

    Author(s) Name:

    V. Lavanya, Dhanraj Ganapathy*, R. M. Visalakshi

    Affiliation(s) Name:

    Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. Dhanraj Ganapathy, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    V. Lavanya, Dhanraj Ganapathy*, R. M. Visalakshi

    Title:Melatonin in periodontitis
    Journal:Drug Invention Today
    Vol(issue):12 (July)
    Year:2019
    Page No: (1482-1485)
  • Experimental Methods Keywords

    Methodology:Immunological system, Inflammation,Oral cavity, Oxidative stress
    Research Materials:Melatonin

Keywords

Immunological system Inflammation Melatonin Oral cavity Oxidative stress

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