Journal: Inter. J. of Chemical and Analytical Science

Article Id: JPRS-AC-0000391
Title: Spectro-Photometric Determination of Capecitabine In Pharmaceutical formulations
Category: Analytical Chemistry
Section: Research Article
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  • Abstract

    Rapid, simple and sensitive spectrophotometric methods are presented for the determination of Capecitabine. The methods are based on their oxidation and precipitation reactions. In both methods the reactions can be monitored spectrophotometrically by measuring the absorbance of the produced complexes at 520 and 560 nm. The proposed methods have permitted the quantification of Capecitabine over linearity in the range of 10-120 mg/ml and its percentage recovery was found to be 99.65-99.93 %.

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    Author(s) Name:

    Medikondu Kishore1*, M.Jayaprakash2, T.Vijayabhaskarareddy3

    Affiliation(s) Name:

    1Department of Post-Graduation Chemistry, SVRM College and Research center, Nagaram, Guntur (District), Andhra Pradesh, India-522268
    2Executive,NatcoResearchCentre,B-13,IndustrialEstate,Sanathnagar,Hyderabad Andhra Pradesh, India-500018
    3Jr.Manager, Quality Assurance, Dr Reddys Laboratories, Bachupally-FTO-III, Hyderabad Andhra Pradesh, India.

    *Corresponding author.
    Medikondu Kishore
    Department of Post-Graduation Chemistry,
    SVRM College and Research center, Nagaram,
    Guntur (District), Andhra Pradesh, India-522268

    Received on: 20-05-2010; Revised on: 16-06-2010; Accepted on:15-07-2010

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    Author:

    Medikondu Kishore1*, M.Jayaprakash2, T.Vijayabhaskarareddy3

    Title:Spectro-Photometric Determination of Capecitabine In Pharmaceutical formulations
    Journal:Inter. J. of Chemical and Analytical Science
    Vol(issue):1 (October)
    Year:2010
    Page No: (238-241)
  • Experimental Methods Keywords

    Methodology:spectrophotometric methods
    Research Materials:Capecitabine

Keywords

Capecitabine spectrophotometric methods. precipitation reactions statistical analysis recovery studies.

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