Journal: Drug Invention Today

Article Id: JPRS-MSNS-00004219
Title: Comparative evaluation of antibiofilm formation activity of Plectranthus amboinicus extract against Streptococcus mutans
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
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    Aim and Introduction: Biofilms are multimicrobial communities enclosed in self-synthesized polymeric matrices attached to biotic or abiotic surfaces. The biofilm is used to describe the various communities of microorganism attached to a surface. These are made up of microbial substances. Biofilms are highly competitive types, where some exhibit as antibiofilm. These show the characteristic features such as bacterial growth inhibition and exclusion. The present study leads to the synthesis of Plectranthus amboinicus extract and studying the antibiofilm formation against Streptococcus mutans. Materials and Methods: The organism S. mutans was isolated from saliva sample using special media [Mutans- Sanguis agar] and maintained in Tryptose soya agar at 4°C in the Department of Microbiology, Saveetha Dental College and Hospitals. Evaluating the microtiter plate with different concentrations of Plectranthus extract against S. mutans and studying the antibiofilm formation. Results: P. amboinicus extract shows significant of antibiofilm against S. mutans. Conclusion: P. amboinicus extract was found to be 79.43% effective than S. mutans. Thus, by increasing the concentration of P. amboinicus extract in the microtiter plate, the effectiveness of Plectranthus extract against S. mutans can be assessed in future.

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    Author(s) Name:

    S. Umayal, R. V. Geetha*

    Affiliation(s) Name:

    Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: R. V. Geetha, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    S. Umayal, R. V. Geetha*

    Title:Comparative evaluation of antibiofilm formation activity of Plectranthus amboinicus extract against Streptococcus mutans
    Journal:Drug Invention Today
    Vol(issue):12 (October)
    Year:2019
    Page No: (2253-2255)
  • Experimental Methods Keywords

    Methodology:antibiofilm formation activity
    Research Materials:Plectranthus amboinicus

Keywords

Extract Microtiter and antibiofilm Plectranthus amboinicus Streptococcus mutans

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