Journal: Drug Invention Today

Article Id: JPRS-P col-00004223
Title: Genetics as a risk factor in periodontitis – A review
Category: Pharmaceutics
Section: Review Article
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    Periodontitis is a multifactorial disease that causes tooth loss. The complex pathogenesis of periodontitis implies the involvement of a susceptible host and a bacterial challenge. Many studies have provided a valuable contribution to understanding the genetic basis of periodontal disease, but the specific candidate genes of susceptibility are still unknown. In fact, genome-wide studies and screening of single-nucleotide polymorphisms have yielded new genetic information without a definitive solution for the management of periodontal disease. In this manuscript, we provide an overview of the most relevant literature, presenting the main concepts and insights of the strategies that have been emerging to better diagnose and treat periodontal disease based on biomarker analysis and host modulation.

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    Author(s) Name:

    Sharmila Balachandran, Dhanraj Ganapathy*, Visalakshi Ramanathan

    Affiliation(s) Name:

    Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dhanraj Ganapathy, Department of Prosthodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

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    Author:

    Sharmila Balachandran, Dhanraj Ganapathy*, Visalakshi Ramanathan

    Title:Genetics as a risk factor in periodontitis – A review
    Journal:Drug Invention Today
    Vol(issue):12 (October)
    Year:2019
    Page No: (2270-2273)
  • Experimental Methods Keywords

    Methodology:Diagnosis, Genetic predisposition to disease, Periodontitis, Risk factors
    Research Materials:periodontitis

Keywords

Diagnosis Genetic predisposition to disease Periodontitis Risk factors

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