Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000425
Title: Cardiotonic activity from the fruit juice of Punica granatum
Category: Pharmacology
Section: Research Article
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    The Pomegranate (Punica granatum) is a fruit-bearing deciduous shrub. Various parts of this plant is used in the treatment of dyspepsia, bronchitis, hypotensive, throat inflammation, worm etc. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. In the present work fresh juice, dilution 1:1 ( juice: distilled water), dilution 1:2 (juice: distilled water), dilution 1:4 (juice: distilled water) are used to evaluate cardiac activity on hypodynamic frog heart and are labeled as A1, A2 , A3 & A4 respectively and compared with Digoxin (B1) as standard solution. It was found that sample A1 (Undiluted juice) showed better response as compared to the other samples. It has been also shown that Punica granatum has rapid onset of action compared to Digoxin. These preliminary studies confirm the better cardiotonic activity of Punica granatum.

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    Author(s) Name:

    Deorao. M. Awari* 1, V.M. Mute 2 , B.B.Thube 1

    Affiliation(s) Name:

    *1Sitabai Thite College of Pharmacy, Shirur Dist. Pune,India.
    2MAEER’s Maharashtra Institute Of Pharmacy, Pune,India.

    For correspondence: Deorao M.Awari, Department of Pharmacology, Sitabai Thite College of Pharmacy, Shirur, At Post-Shirur-412210, Dist-Pune (M.S.),India

    Received on:15-09-2008; Accepted on :09-12-2008

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    Deorao. M. Awari* 1, V.M. Mute 2 , B.B.Thube 1

    Title:Cardiotonic activity from the fruit juice of Punica granatum
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (February)
    Page No: (182-184)
  • Experimental Methods Keywords

    Methodology:Cardiotonic activity
    Research Materials:Punica granatum


Punica granatum Cardiotonic activity Digoxin

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