Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000426
Title: Toxicity Studies on the Extracts of Amoora rohituka Roxb. Stem
Category: Pharmacology
Section: Research Article
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  • Abstract

    The present communications describes the toxicity of Amoora rohituka Roxb stem on Swiss albino mice. In this study, successively prepared ethyl acetate and dichloromethane extracts from stem bark of Amoora rohituka were administered at 20 and 40 mg/kg doses in mice. Dichloromethane extract at 40 mg/kg, significantly (P<0.05) altered body weight gain, haemoglobin level, RBC and WBC count but the changes in haematological parameters were not clinically significant. Dichloromethane extract also significantly (P<0.05) increased the activity of SGPT, thereby indicating some extent of hepatic cell damage. Ethyl acetate extract did not show any adverse effect at 20 and 40 mg/kg doses.

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    Author(s) Name:

    M. Rezaul Karim*1 and M. Rowshanul Habib1

    Affiliation(s) Name:

    *1Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi-6205, Bangladesh


    For correspondence:M. Rezaul Karim ,Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi- 6205, Bangladesh

    Received on:10-09-2008; Accepted on :04-11-2008

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    Author:

    M. Rezaul Karim*1 and M. Rowshanul Habib1

    Title:Toxicity Studies on the Extracts of Amoora rohituka Roxb. Stem
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (February)
    Year:2009
    Page No: (185-188)
  • Experimental Methods Keywords

    Methodology:Toxicity Studies
    Research Materials:Amoora rohituka

Keywords

Amoora rohituka Ethyl acetate extract Dichloromethane extract Swiss albino mice.

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