Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-0000427
Title: Development and validation of spectrophotometric method for estimation of Etoricoxib in tablet dosage forms
Category: Pharmaceutics
Section: Research Article
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  • Abstract

    A simple, specific, precise and accurate Spectrophotometric method was developed for the determination of Etoricoxib by Spectrophotometric method in tablet dosage forms. Etoricoxib shows absorption maximum at 284 nm. The calibration curve was developed at wavelength 284 nm and validated according to ICH Guidelines. Spectrophotometric method linear response obtained was in the concentration range of 2-24 mg/ml with correlation coefficient 0.9995, recovery of the drug was found to be 99.40% and relative standard deviation was found to be less than 2 % for precision studies. The newly developed methods can be used for routine analysis of Etoricoxib in tablet dosage forms.

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    Author(s) Name:

    V.Juyal1 , M.Chaudhary1, P.Kumar1* , G.Gnanarajan, P K.Yadav

    Affiliation(s) Name:

    *1Department of Pharmaceutical Science SGRR ITS Patel Nagar, Dehradun 248001 (UK),India


    For correspondence:Praveen Kumar.,Department of Pharmaceutical Science SGRR ITS Patel Nagar, Dehradun 248001, (UK),India

    Received on:24-08-2008; Accepted on :09-12-2008

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    Author:

    V.Juyal1 , M.Chaudhary1, P.Kumar1* , G.Gnanarajan, P K.Yadav

    Title:Development and validation of spectrophotometric method for estimation of Etoricoxib in tablet dosage forms
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (February)
    Year:2009
    Page No: (200-202)
  • Experimental Methods Keywords

    Methodology:Development and validation, Spectrophotometric;
    Research Materials:Etoricoxib

Keywords

Etoricoxib; Spectrophotometric; Validation

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