Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000438
Title: Antibacterial Activity of Crude Extracts and Phlorotannin Isolated from the Diatom Cymbella spp.
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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    Antibacterial activity of organic and aqueous extracts from the diatoms Cymbella spp. and it’s isolated phlorotannins, collected from Iraq were carried out against seven different species of pathogenic microorganisms: Staphylococcus aureus, Corynebacterium diphtheriae, Escherichia coli, Proteus mirabilis, Klebsiella pneumonia, Salmonella typhi and
    Pseudomonas aeruginosa using disc diffusion and microdilution assay. All extracts showed antibacterial activity against most tested bacteria except, P. mirabilis. The highest growth inhibition was seen against P. aeruginosa (zone of inhibition: 23 mm in diameter) using the ethanol extract concentration 50 mg/ml; and the highest MIC value was observed against P. aeruginosa (MIC=0.19 mg/ml) using the same extract. The isolated compound (phlorotannin) with a concentration of 50 mg/ml achieved good antibacterial activity against all tested bacteria (zone of inhibition range: 9-25 mm) and MIC values in range: 1.56 - >3.12 mg/ml.

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    Author(s) Name:

    Hassan F. Al-Mola

    Affiliation(s) Name:

    Department of Biology, College of Education, University of Mosul, Mosul, Iraq. 

    corresponding authors:Hassan F. Al-Mola
    Department of Biology, College of Education, University of Mosul, Mosul, Iraq.


    Received on:12-12-2008; Accepted on :03-01-2009

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    Author:

    Hassan F. Al-Mola

    Title:Antibacterial Activity of Crude Extracts and Phlorotannin Isolated from the Diatom Cymbella spp.
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (March)
    Year:2009
    Page No: (304-308)
  • Experimental Methods Keywords

    Methodology:Antibacterial activity
    Research Materials:Diatom Cymbella spp

Keywords

Diatoms Antibacterial activity Phlorotannin

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