Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-000044
Title: Pharmacological evaluation of Solanum surattense leaves for antiulcer activity
Category: Pharmacognosy and Herbal Drugs related study
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  • Abstract

    The extracts of petroleum ether, chloroform, alcohol and aqueous of Solanum surattense Burm .f. (Solanaceae) leaves were screened for antiulcer activity by assessing various parameters like pH, free acidity, total acidity and ulcer index. All the extracts were given at dose of 100 mg/kg, b.w. Antiulcer effects were compared with standard drug Omeprazole (20 mg/kg, b.w., p.o.). These observations enable us to conclude that the alcohol extract of Solanum surattense leaves showed predominantly significant activity on acid secretory mechanisms in all parameters as compared to other extracts.

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    Author(s) Name:

    Yogendr Bahuguna*1, Vijay Juyal1, Kuldeep Gusain1

    Affiliation(s) Name:

    1Department of Pharmacognosy & Phytochemistry, Division of Pharmaceutical Sciences, SGRRITS, Patel Nagar, Dehradun, Uttarakhand, India


    For correspondence:Yogendr M. Bahuguna, Department of Pharmacognosy and Phytochemistry,Division of Pharmaceutical Sciences,SGRR Institute of Technology and Sciences, Patel Nagar, Dehradun-248 001, Uttarakhand, India.


    E-mail:yogendr.bahuguna@gmail.com


    Received on: 19-08-2008; Accepted on :17-09-2008

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    Author:

    Yogendr Bahuguna*1, Vijay Juyal1, Kuldeep Gusain1

    Title:Pharmacological evaluation of Solanum surattense leaves for antiulcer activity
    Journal:Journal of Pharmacy Research
    Vol(issue):1(2)
    Year:2008
    Page No: (253-259)
  • Experimental Methods Keywords

    Methodology:Aspirin induced ulcers, Pylorus legation induced gastric ulcers,Determination of Free Acidity and Total Acidity,Ulcer Scoring & Ulcer Index Determination
    Research Materials:Solanum surattense

Keywords

Antiulcer; Solanum surattense; Omeprazole.

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