Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004505
Title: Clinical treatment of rabbits experimentally infected with Staphylococcus aureus using different antibiotics
Category: Pharmacology
Section: Research Article
  • Abstract
  • Audio Abstract
  • Authors
  • Pdf File
  • Citation
  • My Reference
  • Methodology
  • Abstract

    Background: The recurrent bacterial strains antibiotic-resistant is a dangerous problem that has been interfere with human and animal’s public health. The bacteria have permanently the aptitude to keep themselves from the antibiotics that used by the ways of getting resistance through the interchange of the genetic materials with another bacterium. The problematic has been heightened as the occurrence of resistant of bacteria to the antibiotic has increased, and multiply drug-resistant strains have arisen in numerous species that cause illness in humans as well as animals. Materials and Methods: A 30 local rabbits were used in the present study to evaluate the most efficient antibiotic that treats the Staphylococcus aureus infection. These rabbits were divided randomly into six groups, each group contain five rabbits, all groups (except G6) were infected experimentally with 1 ml intraperitoneal of bacterial suspension containing 1 × 108 cfu/ml of viable virulent S. aureus then treated each group with different antibiotic 10% gentamycin 0.5 ml for G1, ceftiofur 5% 0.5 ml for G2, florfenicol 20% 0.5 ml for G3, oxytetracycline 20% 0.5 ml, all given intramuscular after 7 days post-infection for once daily for 3 consequence days, G5 used as control positive, and G6 used as control negative. Results: The results showed that all rabbits in G2 and G3 were cured after using florfenicol and ceftiofur, respectively, while G1 showed two rabbits cured, and there was a resistance of S. aureus for oxytetracycline used in G4. Conclusion: Ceftiofur as well as florfenicol can be used in the treatment of infection with S. aureus.

  • Abstract Audio

    No Audio file found

  • About the authors and Affiliations

    Author(s) Name:

    Mohammad Hamid Kareem1 , Aula Hassoon Obaid2 , Amanee Mohammed Radhy3 , Mustafa Salah Hasan1 *

    Affiliation(s) Name:

    1 Department of Internal and Preventive Medicine, College of Veterinary Medicine, University of Fallujah, Fallujah, Iraq,

    2 Department of Pharmacology, College of Veterinary Medicine, University of Fallujah, Fallujah, Iraq,

    3 Department of Internal and Preventive Medicine, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq

    *Corresponding author: Mustafa Salah Hasan, College of Veterinary Medicine, University of Fallujah, Fallujah, Iraq.

  • View Article File in pdf format.

    Article File
  • View Article Citation Here.

    0 View More
  • How to Cite my Article.

    Author:

    Mohammad Hamid Kareem1 , Aula Hassoon Obaid2 , Amanee Mohammed Radhy3 , Mustafa Salah Hasan1 *

    Title:Clinical treatment of rabbits experimentally infected with Staphylococcus aureus using different antibiotics
    Journal:Drug Invention Today
    Vol(issue):12 (November )
    Year:2019
    Page No: (2832-2834)
  • Experimental Methods Keywords

    Methodology:Clinical treatment , infected with Staphylococcus aureus
    Research Materials:Ceftiofur, Florfenicol, Gentamycin, Oxytetracycline

Keywords

Ceftiofur Florfenicol Gentamycin Oxytetracycline Staphylococcus aureus

Our Services

Most Downloaded List