Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000456
Title: Antioxidant activity of ethanolic extract of Piper betel leaves
Category: Pharmacognosy and Herbal Drugs related study
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  • Abstract

    The present study was aimed to investigate the antioxidant activity of methanolic extracts of Piper betel leaves by different methods like DPPH photometric assay, reductive ability, Deoxyribose degradation assay and Superoxide scavenging activity. It belongs to the family Piperaceae used as ingredients in a chew commonly known as pan. Chemically Piper betel containing chavi betel, chavicol, betel oil, terpene, sesquiterpene. Biologically Piper betel have broad spectrum activities like antifungal, antibacterial, antitumour, hypotensive, respiratory depressant, anthelmintic, cardiotonic and antifertility. PBLE showed strong antioxidant activities like reducing power, DPPH radical, superoxide anion scavenging and deoxyribose degradation activities when compared with different standards such as ascorbic acid, DMSO and BHT. Presumably, PBLE functions as an antioxidant to scavenge free radicals and reduces free radical induced cell injury.

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    Author(s) Name:

    Ashish Manigauha 1*, Huma Ali 2 and M. Uma maheshwari 3

    Affiliation(s) Name:

    *1 NRI Institute of Pharmacy, Sajjan Singh Nagar, Raisen Road, Bhopal – 462021 (India)
    2Dept. of Research, Jawaharlal Nehru Cancer Hospital & Research Center, Bhopal- 462001
    3College of Pharmacy, Sri Ramkrishna Institute of Paramedical Sciences, Coimbatore, Tamilnadu. India


    For correspondence: Ashish Manigauha ,Department of Pharmacology and Phytochemistry, NRI Institute of Pharmacy, Sajjan Singh Nagar, Raisen Road, Bhopal – 462021 (India)

    Received on:25-08-2008; Accepted on :09-01-2009

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    Author:

    Ashish Manigauha 1*, Huma Ali 2 and M. Uma maheshwari 3

    Title:Antioxidant activity of ethanolic extract of Piper betel leaves
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (March)
    Year:2009
    Page No: (491-494)
  • Experimental Methods Keywords

    Methodology:Antioxidant, DPPH, Reducing power
    Research Materials:Piper betel

Keywords

Piper betel leaves extract Antioxidant DPPH Reducing power DMSO

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