Journal: Journal of Pharmacy Research

Article Id: JPRS-PCS-0000458
Title: Simultaneous estimation of Tamsulosin hydrochloride and Dutasteride in combined dosage form by UV spectroscopy method
Category: Pharmaceutics
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    Fixed dose combination tablets containing Tamsulosin hydrochloride & Dutasteride are used to treat the symptoms of an enlarged prostate, a condition technically known as benign prostatic hyperplasia or BPH. Several chromatographic methods have been reported for simultaneous estimation of these drugs and individual drug. The drugs individually and in mixture obeys Beer‘s law over conc. range 0.0347 mg/mL for Tamsulosin hydrochloride (TAM) and for Dutasteride 0.012 mg/mL (DUTA). The mean recoveries from tablet by standard addition method were 99.0% and 99.5 %. The present work reports simple, accurate and precise spectrophotometric method for the simultaneous estimation of Tamsulosin hydrochloride and Dutasteride in combined from tablet dosage form.

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    Author(s) Name:

    Pande V.V.*, Jadhav J.N.,* Chandorkar J.G.**

    Affiliation(s) Name:

    * JSPM’s, Jaywantrao Sawant College of Pharmacy & Research, S.No.58, Satavnagar, Handewadi Road, Hadapsar, Pune-411028,India.
    ** Innovassynth Technologies Ltd, Khopoli, Dist. Raigad.India.


    For correspondence:Pande V.V,JSPM’s,Department of Pharmacutical Chemistry, Jaywantrao Sawant College of Pharmacy & Research, S.No.58, Satavnagar,Handewadi Road, Hadapsar, Pune-411028,India.


    Received on:19-08-2008; Accepted on :15-02-2009

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    Author:

    Pande V.V.*, Jadhav J.N.,* Chandorkar J.G.**

    Title:Simultaneous estimation of Tamsulosin hydrochloride and Dutasteride in combined dosage form by UV spectroscopy method
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (March)
    Year:2009
    Page No: (507-509)
  • Experimental Methods Keywords

    Methodology:UV spectroscopy method
    Research Materials:Tamsulosin hydrochloride and Dutasteride

Keywords

Tamsulosin hydrochloride (TAM) Dutasteride (DUTA) Benign prostatic hyperplasia or BPH

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