Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000465
Title: Nardostachys jatamansi: cardioprotective and hypolipidemic herb
Category: Pharmacology
Section: Research Article
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    Nardostachys jatamansi belongs to the family Valerianaceae. It is commonly used as a folk medicine for hypolipidemic activity. This made us to evaluate the hypolipidemic and cardioprotective activity in isoproterenol and triton WR 1339 administered diseased animals. Pretreatment of isoproterenol administered animals with 50 mg/kg b.wt, of Nardostachys jatamansi was found to exhibit a better antioxidant and hypolipidemic activity. Mild changes in cardiac markers reveal that the dose of Nardostachys jatamansi should be increased. In triton WR 1339 induced hyperlipidemic rats, administration of 1000 mg/kg b.wt. of extract for seven days showed the hypolipidemic activity.

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    Author(s) Name:

    Gayathri Krishnamoorthy, Mohamed M. Shabi, Dhevi Ravindhran, Subasini Uthrapathy, *Victor G. Rajamanickam, Govindha P. Dubey

    Affiliation(s) Name:

    *Centre for Advanced Research in Indian System of Medicine (CARISM),SASTRA University, Thanjavur 613 402, India


    Received on: 05-09-2008; Accepted on: 24-02-2009

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    Author:

    Gayathri Krishnamoorthy, Mohamed M. Shabi, Dhevi Ravindhran, Subasini Uthrapathy, *Victor G. Rajamanickam, Govindha P. Dubey

    Title:Nardostachys jatamansi: cardioprotective and hypolipidemic herb
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (April)
    Year:2009
    Page No: (574-578)
  • Experimental Methods Keywords

    Methodology:cardioprotective and hypolipidemic activity
    Research Materials:Nardostachys jatamansi

Keywords

Isoproterenol Triton WR 1339 cardiac markers lipid profile antioxidant

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