Journal: Journal of Pharmacy Research
Title: In-vitro anti-arthritic activity of Abutilon indicum (Linn.) Sweet
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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Abstract
Rheumatoid arthritis is a major ailment among rheumatic disorders. A large number of herbal extracts are in vogue used for treatment of various types of rheumatic disorders. Abutilon indicum (Linn.) Sweet, an Indian herb was reported to have anti-inflammatory as well as analgesic activity, in-vitro as well as in-vivo. The present study deals with anti-arthritic activity in-vitro. Various in-vitro anti-arthritic pharmacological models were studied, such as, inhibition of protein denaturation, effect of membrane stabilization, and proteinase inhibitory action.Herbal extract (aq.) with two different concentrations (100mcg/ml and 250mcg/ml.) was used and results were compared with acetyl salicylic acid (250mcg/ml.). The herbal extract showed dose dependent activity which was found to be better than that of acetyl salicylic acid.
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About the authors and Affiliations
Author(s) Name: Mr. Vallabh Deshpande*, Dr. (Mrs.) Varsha M.Jadhav, Dr.V.J.Kadam.
Affiliation(s) Name: *Bharati Vidhyapeeth College of Pharmacy, Navi Mumbai, Sector 8, CBD Belapur. Maharastra, India.
*For correspondence: Mr. Vallabh Deshpande
Received on:16-12-2008; Accepted on :25-02-2009-
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Author: Mr. Vallabh Deshpande*, Dr. (Mrs.) Varsha M.Jadhav, Dr.V.J.Kadam.
Title: In-vitro anti-arthritic activity of Abutilon indicum (Linn.) Sweet Journal: Journal of Pharmacy Research Vol(issue): 2 (April) Year: 2009 Page No: (644-645) -
Experimental Methods Keywords
Methodology: Anti-arthritic, Anti-inflammatory, Proteinase inhibitory, protein denaturation, Membrane Research Materials: Abutilon indicum (Linn.)
Keywords
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