Journal: Journal of Pharmacy Research

Article Id: JPRS-PHDRS-0000473
Title: In-vitro anti-arthritic activity of Abutilon indicum (Linn.) Sweet
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
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  • Abstract

    Rheumatoid arthritis is a major ailment among rheumatic disorders. A large number of herbal extracts are in vogue used for treatment of various types of rheumatic disorders. Abutilon indicum (Linn.) Sweet, an Indian herb was reported to have anti-inflammatory as well as analgesic activity, in-vitro as well as in-vivo. The present study deals with anti-arthritic activity in-vitro. Various in-vitro anti-arthritic pharmacological models were studied, such as, inhibition of protein denaturation, effect of membrane stabilization, and proteinase inhibitory action.Herbal extract (aq.) with two different concentrations (100mcg/ml and 250mcg/ml.) was used and results were compared with acetyl salicylic acid (250mcg/ml.). The herbal extract showed dose dependent activity which was found to be better than that of acetyl salicylic acid.

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  • About the authors and Affiliations

    Author(s) Name:

    Mr. Vallabh Deshpande*, Dr. (Mrs.) Varsha M.Jadhav, Dr.V.J.Kadam.

    Affiliation(s) Name:

    *Bharati Vidhyapeeth College of Pharmacy, Navi Mumbai, Sector 8, CBD Belapur. Maharastra, India.


    *For correspondence: Mr. Vallabh Deshpande

    Received on:16-12-2008; Accepted on :25-02-2009

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    Author:

    Mr. Vallabh Deshpande*, Dr. (Mrs.) Varsha M.Jadhav, Dr.V.J.Kadam.
    Title:In-vitro anti-arthritic activity of Abutilon indicum (Linn.) Sweet
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (April)
    Year:2009
    Page No: (644-645)

  • Experimental Methods Keywords

    Methodology:Anti-arthritic, Anti-inflammatory, Proteinase inhibitory, protein denaturation, Membrane
    Research Materials:Abutilon indicum (Linn.)

Keywords

Abutilon indicum (Linn.) Sweet Anti-arthritic Anti-inflammatory Proteinase inhibitory protein denaturation Membrane

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