Article Id:JPRS-PHDRS-0000473 Title:In-vitro anti-arthritic activity of Abutilon indicum (Linn.) Sweet Category:Pharmacognosy and Herbal Drugs related study Section:Research Article
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Rheumatoid arthritis is a major ailment among rheumatic disorders. A large number of herbal extracts are in vogue used for treatment of various types of rheumatic disorders. Abutilon indicum (Linn.) Sweet, an Indian herb was reported to have anti-inflammatory as well as analgesic activity, in-vitro as well as in-vivo. The present study deals with anti-arthritic activity in-vitro. Various in-vitro anti-arthritic pharmacological models were studied, such as, inhibition of protein denaturation, effect of membrane stabilization, and proteinase inhibitory action.Herbal extract (aq.) with two different concentrations (100mcg/ml and 250mcg/ml.) was used and results were compared with acetyl salicylic acid (250mcg/ml.). The herbal extract showed dose dependent activity which was found to be better than that of acetyl salicylic acid.